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2010 Mercedes-Benz S600 (W221)
Shown: 2010 Mercedes-Benz S600 (W221). Photo: Elise240SX, CC BY-SA 4.0, via Wikimedia Commons
  • Newest year: 2013
  • Gas
  • Hybrid
  • Large cars

2007-2013 Mercedes-Benz S-Class MPG & Fuel Cost

7 model years · 13–21 MPG combined

19 MPG
Combined
15 MPG
City
25 MPG
Highway
Annual fuel cost · S550 4.7L 8-cyl turbo RWD
$4,340

15,000 mi/yr · premium gasoline $5.36/gal (U.S. average, Sep 2026)

Cheaper to fuel than 2 of 10 large car configurations, MY2013. Ranked against all rated configurations, not sales-weighted.

2007-2013 Mercedes-Benz S-Class at a glance

The 2007-2013 Mercedes-Benz S-Class covers 7 model years in the EPA database (38 configurations in all), rated 13–21 MPG combined. The newest model year, 2013, costs about $3,820 a year to fuel for its most efficient version, the S400 Hybrid 3.5L 6-cyl RWD (21 MPG), at premium gasoline $5.36/gal (U.S. average, Sep 2026). Powertrains over the years: gas and hybrid. EPA changed the ratings in 2008, 2009, 2010, 2011, 2012 and 2013. The best combined rating in the generation, 21 MPG, was reached in 2010, 2011, 2012 and 2013.

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

2007-2013 Mercedes-Benz S-Class by model year

2007-2013 Mercedes-Benz S-Class: EPA combined rating and yearly fuel cost for each model year
Model yearPowertrainsCombined$/yrEPA ratings
2013 Gas, Hybrid 14–21 MPG $3,820–$5,630 Ratings changed
2012 Gas, Hybrid 14–21 MPG $3,820–$5,630 Ratings changed
2011 Gas, Hybrid 14–21 MPG $3,820–$5,630 Ratings changed
2010 Gas, Hybrid 13–21 MPG $3,830–$6,180 Ratings changed
2009 Gas 13–17 MPG $4,730–$6,180 Ratings changed
2008 Gas 13–16 MPG $5,020–$6,180 Ratings changed
2007 Gas 13–17 MPG $4,730–$6,180 First year

What the 2013 S550 4.7L 8-cyl turbo RWD costs to drive

Per month

$362

$4,340 a year ÷ 12

Per 25 miles

$7.23

Per 100 miles

$28.93

Five years

$21,700

5 × the yearly cost, prices held at today's level

vs the large car median

$520more a year

Class median $3,820 a year, MY2013

Based on 15,000 miles a year and premium gasoline $5.36/gal (U.S. average, Sep 2026).

2013 Mercedes-Benz S-Class MPG

Versus 2012: The most efficient configuration stays at 21 MPG. Its annual cost stays at $3,820.

Gas · 4.7L, 5.5L, 6.0L
Combined
14–19 MPG
Per year
$4,340–$5,630
See gas configurations
Hybrid · 3.5L
Combined
21 MPG
Per year
$3,820
See hybrid configurations

Gas configurations (5)

2013 Mercedes-Benz S-Class gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
S550 (Most efficient) 4.7L 8-cyl turbo RWD 15 25 19 $4,340
S550 4matic 4.7L 8-cyl turbo 4WD 15 24 18 $4,530
S63 AMG 5.5L 8-cyl turbo RWD 15 23 18 $4,540
S65 AMG 6.0L 12-cyl turbo RWD 12 19 15 $5,530
S600 5.5L 12-cyl turbo RWD 12 19 14 $5,630

5 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

Hybrid configurations (1)

2013 Mercedes-Benz S-Class hybrid configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
S400 Hybrid (Most efficient) 3.5L 6-cyl RWD 19 25 21 $3,820

1 configuration requires or recommends higher-octane gasoline and is costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2012 Mercedes-Benz S-Class MPG

14–21 MPG · $3,820–$5,630/yr

Versus 2011: The most efficient configuration stays at 21 MPG. Its annual cost stays at $3,820.

Gas · 4.7L, 5.5L, 6.0L
Combined
14–19 MPG
Per year
$4,340–$5,630
See gas configurations
Hybrid · 3.5L
Combined
21 MPG
Per year
$3,820
See hybrid configurations

Gas configurations (5)

2012 Mercedes-Benz S-Class gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
S550 (Most efficient) 4.7L 8-cyl turbo RWD 15 25 19 $4,340
S63 AMG 5.5L 8-cyl turbo RWD 15 23 18 $4,540
S550 4matic 4.7L 8-cyl turbo 4WD 15 24 18 $4,540
S65 AMG 6.0L 12-cyl turbo RWD 12 19 15 $5,530
S600 5.5L 12-cyl turbo RWD 12 19 14 $5,630

5 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

Hybrid configurations (1)

2012 Mercedes-Benz S-Class hybrid configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
S400 Hybrid (Most efficient) 3.5L 6-cyl RWD 19 25 21 $3,820

1 configuration requires or recommends higher-octane gasoline and is costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2011 Mercedes-Benz S-Class MPG

14–21 MPG · $3,820–$5,630/yr

Versus 2010: The most efficient configuration stays at 21 MPG. Its annual cost goes from $3,830 to $3,820, $10 less.

Gas · 5.5L, 6.0L
Combined
14–18 MPG
Per year
$4,490–$5,630
See gas configurations
Hybrid · 3.5L
Combined
21 MPG
Per year
$3,820
See hybrid configurations

Gas configurations (5)

2011 Mercedes-Benz S-Class gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
S550 (Most efficient) 5.5L 8-cyl RWD 15 23 18 $4,490
S63 AMG 5.5L 8-cyl turbo RWD 15 22 18 $4,590
S550 4matic 5.5L 8-cyl 4WD 14 21 17 $4,800
S65 AMG 6.0L 12-cyl turbo RWD 12 19 14 $5,540
S600 5.5L 12-cyl turbo RWD 12 19 14 $5,630

5 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

Hybrid configurations (1)

2011 Mercedes-Benz S-Class hybrid configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
S400 Hybrid (Most efficient) 3.5L 6-cyl RWD 19 25 21 $3,820

1 configuration requires or recommends higher-octane gasoline and is costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2010 Mercedes-Benz S-Class MPG

13–21 MPG · $3,830–$6,180/yr

Versus 2009: The most efficient configuration moves from 17 to 21 MPG, up 4. Its annual cost goes from $4,730 to $3,830, $900 less.

Gas · 5.5L, 6.0L, 6.3L
Combined
13–18 MPG
Per year
$4,460–$6,180
See gas configurations
Hybrid · 3.5L
Combined
21 MPG
Per year
$3,830
See hybrid configurations

Gas configurations (5)

2010 Mercedes-Benz S-Class gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
S550 (Most efficient) 5.5L 8-cyl RWD 15 23 18 $4,460
S550 4matic 5.5L 8-cyl 4WD 14 21 17 $4,730
S63 AMG 6.3L 8-cyl RWD 11 18 14 $5,740
S600 5.5L 12-cyl turbo RWD 11 17 13 $6,180
S65 AMG 6.0L 12-cyl turbo RWD 11 17 13 $6,180

5 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

Hybrid configurations (1)

2010 Mercedes-Benz S-Class hybrid configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
S400 Hybrid (Most efficient) 3.5L 6-cyl RWD 19 25 21 $3,830

1 configuration requires or recommends higher-octane gasoline and is costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2009 Mercedes-Benz S-Class MPG

13–17 MPG · $4,730–$6,180/yr

Versus 2008: The most efficient configuration moves from 16 to 17 MPG, up 1. Its annual cost goes from $5,020 to $4,730, $290 less.

Gas · 5.5L, 6.0L, 6.2L
Combined
13–17 MPG
Per year
$4,730–$6,180

Gas configurations (5)

2009 Mercedes-Benz S-Class gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
S550 (Most efficient) 5.5L 8-cyl RWD 14 22 17 $4,730
S550 4matic 5.5L 8-cyl 4WD 14 21 17 $4,730
S600 5.5L 12-cyl turbo RWD 11 17 13 $6,180
S63 AMG 6.2L 8-cyl RWD 11 17 13 $6,180
S65 AMG 6.0L 12-cyl turbo RWD 11 17 13 $6,180

5 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2008 Mercedes-Benz S-Class MPG

13–16 MPG · $5,020–$6,180/yr

Versus 2007: The most efficient configuration moves from 17 to 16 MPG, down 1. Its annual cost goes from $4,730 to $5,020, $290 more.

Gas · 5.5L, 6.0L, 6.2L
Combined
13–16 MPG
Per year
$5,020–$6,180

Gas configurations (5)

2008 Mercedes-Benz S-Class gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
S550 (Most efficient) 5.5L 8-cyl RWD 14 21 16 $5,020
S550 4matic 5.5L 8-cyl 4WD 14 20 16 $5,020
S63 AMG 6.2L 8-cyl RWD 11 17 13 $6,180
S600 5.5L 12-cyl turbo RWD 11 17 13 $6,180
S65 AMG 6.0L 12-cyl turbo RWD 11 17 13 $6,180

5 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2007 Mercedes-Benz S-Class MPG

13–17 MPG · $4,730–$6,180/yr

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

Gas · 5.5L, 6.0L
Combined
13–17 MPG
Per year
$4,730–$6,180

Gas configurations (4)

2007 Mercedes-Benz S-Class gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
S550 (Most efficient) 5.5L 8-cyl RWD 14 22 17 $4,730
S550 4matic 5.5L 8-cyl 4WD 14 21 16 $5,020
S65 AMG 6.0L 12-cyl turbo RWD 11 18 14 $5,740
S600 5.5L 12-cyl turbo RWD 11 17 13 $6,180

4 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

Fuel cost by state

Yearly cost of the S550 4.7L 8-cyl turbo RWD: $5,170 in California and $3,760 in Texas, a $1,410 difference.

Gasoline prices: California: California state average; Washington: Washington state average; New York: New York state average; Florida: Florida state average; Texas: Texas state average (Sep 2026).
Fuel cost in every state

Similar cars

Closest combined MPG among MY2013 large car models.

EPA ratings: fueleconomy.gov file of Sep 29, 2026 · Prices: EIA regular gasoline, U.S. average, Sep 2026 ($4.36/gal) · 15,000 mi/yr, 55% city / 45% highway · How we calculate

Generations

Frequently asked questions

What gas mileage does the 2007-2013 Mercedes-Benz S-Class get?

EPA rates the 2007-2013 Mercedes-Benz S-Class at 13–21 MPG combined across 38 configurations and 7 model years. The most efficient version, the 2013 S400 Hybrid 3.5L 6-cyl RWD, is rated 21 MPG (19 city, 25 highway). By powertrain: Gas: 13–19 MPG; Hybrid: 21 MPG.

Which years had the best MPG in the 2007-2013 Mercedes-Benz S-Class?

The S400 Hybrid 3.5L 6-cyl RWD reached the generation's best combined rating, 21 MPG, in 2010, 2011, 2012 and 2013. The lowest top rating, 16 MPG, was in 2008.

Did EPA ratings change during the 2007-2013 Mercedes-Benz S-Class?

Yes. Ratings changed in 2008, 2009, 2010, 2011, 2012 and 2013.

How does the 2007-2013 Mercedes-Benz S-Class compare with the previous generation?

The previous generation (2000-2006 Mercedes-Benz S-Class) is rated 13–19 MPG combined and costs $4,230–$6,180 a year to fuel; the 2007-2013 model is rated 13–21 MPG and costs $3,820–$6,180 a year.

How much does it cost to fuel a 2013 Mercedes-Benz S-Class per year?

Driving 15,000 miles a year at premium gasoline $5.36/gal (U.S. average, Sep 2026), the S550 4.7L 8-cyl turbo RWD costs about $4,340 a year. Across all 6 configurations the cost runs $3,820–$5,630 a year. That is a $1,810 difference between the cheapest and the costliest configuration.

How much does it cost to drive a 2013 Mercedes-Benz S-Class 100 miles?

About $28.93 per 100 miles for the S550 4.7L 8-cyl turbo RWD at premium gasoline $5.36/gal (U.S. average, Sep 2026), and between $25.47 and $37.53 across all configurations. That is the annual cost over 15,000 miles divided by 150.

How does the 2013 Mercedes-Benz S-Class compare with other large car configurations?

The S550 4.7L 8-cyl turbo RWD costs about $4,340 a year to fuel, $520 more than the class median of $3,820, and less than 2 of 10 large car configurations. The comparison covers all 93 rated large car configurations for MY2013, not weighted by sales.

Is the 2013 Mercedes-Benz S-Class hybrid cheaper to fuel than the gas version?

Yes. The best hybrid (S400 Hybrid 3.5L 6-cyl RWD) is rated 21 MPG against 19 MPG for the best gas version (S550 4.7L 8-cyl turbo RWD), 2 MPG more. At premium gasoline $5.36/gal (U.S. average, Sep 2026) that is $3,820 versus $4,340 a year, a saving of $520.

Is the 2013 Mercedes-Benz S-Class different from the 2012 model?

The most efficient configuration stays at 21 MPG. Its annual cost stays at $3,820. EPA lists 6 configurations for 2013 against 6 configurations for 2012. See the 2012 Mercedes-Benz S-Class for that year.