2004-2008 Ford F-150 MPG & Fuel Cost

EPA rates the 2004-2008 Ford F-150 at 13–16 MPG combined across 49 configurations and 5 model years. The most efficient version, the 2008 Pickup 4.2L 6-cyl RWD, is rated 16 MPG (14 city, 19 highway). By powertrain: Gas: 13–16 MPG; Natural gas: 12–13 MPGe.

The Pickup 4.2L 6-cyl RWD reached the generation's best combined rating, 16 MPG, in 2004, 2006, 2007 and 2008. The lowest top rating, 15 MPG, was in 2005.

Yes. Ratings changed in 2005, 2006, 2007 and 2008.

The previous generation (2000-2003 Ford F-150) is rated 12–17 MPG combined and costs $3,840–$6,700 a year to fuel; the 2004-2008 model is rated 13–16 MPG and costs $4,080–$6,180 a year.

Driving 15,000 miles a year at regular gasoline $4.36/gal (U.S. average, Sep 2026), the Pickup 4.2L 6-cyl RWD costs about $4,080 a year. Across all 10 configurations the cost runs $4,080–$4,670 a year. That is a $590 difference between the cheapest and the costliest configuration.

About $27.20 per 100 miles for the Pickup 4.2L 6-cyl RWD at regular gasoline $4.36/gal (U.S. average, Sep 2026), and between $27.20 and $31.13 across all configurations. That is the annual cost over 15,000 miles divided by 150.

The Pickup 4.2L 6-cyl RWD is rated 14 city and 19 highway MPG, so it is more efficient on the highway, by 5 MPG.

The Pickup 4.2L 6-cyl RWD costs about $4,080 a year to fuel, $280 less than the class median of $4,360, and less than 7 of 10 standard pickup configurations. The comparison covers all 85 rated standard pickup configurations for MY2008, not weighted by sales.

The most efficient configuration stays at 16 MPG. Its annual cost stays at $4,080. EPA lists 10 configurations for 2008 against 10 configurations for 2007. See the 2007 Ford F-150 for that year.