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  • Hybrids and plug-ins
  • MY2006

Most Fuel-Efficient Hybrids of 2006

The most efficient 2006 hybrid is the Honda Insight (1.0 L · FWD) at 52 MPG combined, 25 MPG above the median hybrid (27 MPG) among the 11 hybrids ranked. The Honda Insight costs about $1,260 a year to fuel, $1,160 less than the median hybrid ($2,420).

The top 10 run from 52 MPG to 17 MPG. Each model is listed once, with its best qualifying configuration named in the row; models with the same displayed value share a rank.

Best combined

52MPG

Honda Insight

Median model

27MPG

11 models

Top-10 median

27MPG

Models ranked

11

one row per model

Full ranking

All 11 models. Every column is sortable.

Most Fuel-Efficient Hybrids of 2006: top 11 of 11 models
1
Honda Insight
1.0 L · FWD
Two-seaters · Hybrid
524858$1,260+25
2
Toyota Prius
1.5 L · FWD
Midsize cars · Hybrid
464845$1,420+19
3
Honda Civic
Hybrid · 1.3 L · FWD
Small cars · Hybrid
424045$1,560+15
4
Ford Escape
Hybrid · 2.3 L · FWD
Standard SUVs · Hybrid
293028$2,250+2
5
Lexus RX
400h · 3.3 L · FWD
Standard SUVs · Hybrid
272825$2,4200
5
Mazda Tribute
Hybrid · 2.3 L
Standard SUVs · Hybrid
272826$2,4200
5
Mercury Mariner
Hybrid · 2.3 L
Standard SUVs · Hybrid
272826$2,4200
5
Toyota Highlander
Hybrid · 3.3 L · FWD
Standard SUVs · Hybrid
272825$2,4200
9
Honda Accord
Hybrid · 3.0 L · FWD
Midsize cars · Hybrid
252231$2,610−2
10
Chevrolet Silverado
15 Hybrid · 5.3 L · RWD
Standard pickups · Hybrid
171619$3,840−10
10
GMC Sierra
15 Hybrid · 5.3 L · RWD
Standard pickups · Hybrid
171619$3,840−10

How this list is built

Every line below is read from the list definition that produced the table.

  • Classes: every EPA class except special-purpose vehicles.
  • Powertrains: Hybrid.
  • Ranked by EPA combined MPG, highest first.
  • One row per model (make and model): the configuration that ranks best in this list is shown, with its trim, engine and drive named in the row.
  • Ties are decided on the displayed value (whole MPG or miles, kWh per 100 miles to one decimal, cost rounded to $10): tied models share a rank, then are ordered by a tie-breaker and by name.
  • Special-purpose vehicles, such as heavy-duty variants, are excluded.
  • Electric vehicles are ranked separately (see the EV rankings): gas, hybrid and diesel MPG is never mixed with MPGe.
  • Annual cost assumes 15,000 miles a year at the EPA rating and the dated national fuel prices stamped below; it is rounded to $10 and all differences use the rounded values.
  • Model years MY2006 to MY2027; a year is listed only when at least 10 models qualify.

Data and period

  • EPA ratings: fueleconomy.gov file of Sep 29, 2026
  • Prices: EIA regular gasoline, U.S. average, Sep 2026 ($4.36/gal); residential electricity, U.S. average, Jul 2026 (18.3¢/kWh)
  • 15,000 miles a year, 55% city and 45% highway

Frequently asked questions

Which 2006 hybrid gets the best gas mileage?

The most efficient 2006 hybrid is the Honda Insight (1.0 L · FWD) at 52 MPG combined, 25 MPG above the median hybrid (27 MPG) among the 11 hybrids ranked. The Honda Insight costs about $1,260 a year to fuel, $1,160 less than the median hybrid ($2,420).

How much does the Honda Insight cost to fuel per year?

About $1,260 a year at 15,000 miles a year, using the prices stamped at the bottom of this page. The median hybrid in this list costs $2,420 a year.

How many hybrids are ranked for 2006?

11 models qualify, one row each. The median is 27 MPG, and the top 10 run from 52 MPG to 17 MPG.

How are ties, trims and drivetrains handled?

Each model appears once, with the configuration that ranks best in this list; its trim, engine and drive are named in the row. Models with the same displayed value share a rank (1, 2, 2, 4) and are then ordered by a tie-breaker and by name. See the methodology.

Are electric cars and plug-in hybrids included?

Not in this list. MPG rankings cover gas, hybrid and diesel models only. Electric cars are ranked in EV range and EV efficiency, and plug-in hybrids in electric range.

What does combined MPG mean?

EPA's combined rating blends 55% city and 45% highway driving. It comes from standardized laboratory tests, so your results will differ with driving style, weather and load. See the methodology.

EPA ratings: fueleconomy.gov file of Sep 29, 2026 · Prices: EIA regular gasoline, U.S. average, Sep 2026 ($4.36/gal); residential electricity, U.S. average, Jul 2026 (18.3¢/kWh) · 15,000 miles a year, 55% city and 45% highway