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2004 GMC Sierra 1500 SLE Crew Cab
Shown: 2004 GMC Sierra 1500 SLE Crew Cab. Photo: Cutlass, CC0, via Wikimedia Commons
  • Newest year: 2006
  • Gas
  • Hybrid
  • Standard pickups

2000-2006 GMC Sierra MPG & Fuel Cost

7 model years · 11–18 MPG combined

17 MPG
Combined
15 MPG
City
20 MPG
Highway
Annual fuel cost · 1500 4.3L 6-cyl RWD
$3,840

15,000 mi/yr · regular gasoline $4.36/gal (U.S. average, Sep 2026)

Cheaper to fuel than 6 of 10 standard pickup configurations, MY2006. Ranked against all rated configurations, not sales-weighted.

Next generation: 2007-2013

2000-2006 GMC Sierra at a glance

The 2000-2006 GMC Sierra covers 7 model years in the EPA database (100 configurations in all), rated 11–18 MPG combined. The newest model year, 2006, costs about $3,840 a year to fuel for its most efficient version, the 1500 4.3L 6-cyl RWD (17 MPG), at regular gasoline $4.36/gal (U.S. average, Sep 2026). Powertrains over the years: gas, hybrid and natural gas. EPA changed the ratings in 2001, 2002, 2003, 2004, 2005 and 2006. The best combined rating in the generation, 18 MPG, was reached in 2000.

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

2000-2006 GMC Sierra by model year

2000-2006 GMC Sierra: EPA combined rating and yearly fuel cost for each model year
Model yearPowertrainsCombined$/yrEPA ratings
2006 Gas, Hybrid 13–17 MPG $3,840–$6,180 Ratings changed
2005 Gas, Hybrid, Natural gas 11–17 MPG, 9 MPGe $3,840–$5,940 Ratings changed
2004 Gas, Hybrid 13–17 MPG $3,840–$5,030 Ratings changed
2003 Gas 13–16 MPG $4,080–$5,030 Ratings changed
2002 Gas 12–16 MPG $4,080–$5,440 Ratings changed
2001 Gas 11–17 MPG $3,840–$5,940 Ratings changed
2000 Gas 12–18 MPG $3,630–$5,440 First year

What the 2006 1500 4.3L 6-cyl RWD costs to drive

Per month

$320

$3,840 a year ÷ 12

Per 25 miles

$6.40

Per 100 miles

$25.60

Five years

$19,200

5 × the yearly cost, prices held at today's level

vs the standard pickup median

$240less a year

Class median $4,080 a year, MY2006

Based on 15,000 miles a year and regular gasoline $4.36/gal (U.S. average, Sep 2026).

2006 GMC Sierra MPG

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

Versus 2005: The most efficient configuration stays at 17 MPG. Its annual cost stays at $3,840.

Gas · 4.3L, 4.8L, 5.3L…
Combined
13–17 MPG
Per year
$3,840–$6,180
See gas configurations
Hybrid · 5.3L
Combined
16–17 MPG
Per year
$3,840–$4,080
See hybrid configurations

Gas configurations (15)

2006 GMC Sierra gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
1500 4.3L 6-cyl RWD Automatic 4-spd (Most efficient) 4.3L 6-cyl RWD 15 20 17 $3,840
1500 4.8L 8-cyl RWD Automatic 4-spd 4.8L 8-cyl RWD 15 19 17 $3,840
1500 4.3L 6-cyl RWD Manual 5-spd 4.3L 6-cyl RWD 14 20 16 $4,080
1500 4.8L 8-cyl RWD Manual 5-spd 4.8L 8-cyl RWD 14 19 16 $4,080
1500 5.3L 8-cyl RWD Automatic 4-spd 5.3L 8-cyl RWD 14 19 16 $4,080
1500 5.3L 8-cyl RWD Automatic 4-spd 5.3L 8-cyl RWD 14 19 16 $4,080
1500 4.3L 6-cyl 4WD Automatic 4-spd 4.3L 6-cyl 4WD 13 17 15 $4,360
1500 4.3L 6-cyl 4WD Manual 5-spd 4.3L 6-cyl 4WD 13 18 15 $4,360
1500 4.8L 8-cyl 4WD Automatic 4-spd 4.8L 8-cyl 4WD 14 18 15 $4,360
1500 4.8L 8-cyl 4WD Manual 5-spd 4.8L 8-cyl 4WD 14 18 15 $4,360
Show 5 more configurations
2006 GMC Sierra gas configurations: EPA ratings and annual cost (+5)
TrimEngineDriveCityHwyComb.$/yr
1500 5.3L 8-cyl 4WD Automatic 4-spd5.3L 8-cyl4WD131815$4,360
1500 5.3L 8-cyl 4WD Automatic 4-spd5.3L 8-cyl4WD131715$4,360
1500 6.0L 8-cyl RWD6.0L 8-cylRWD131815$5,360
1500 6.0L 8-cyl 4WD Automatic 4-spd6.0L 8-cyl4WD131614$5,740
1500 6.0L 8-cyl 4WD Automatic 4-spd6.0L 8-cyl4WD121613$6,180

3 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

Flex-fuel (E85) configurations are costed on gasoline, not E85.

Hybrid configurations (2)

2006 GMC Sierra hybrid configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
15 Hybrid 5.3L 8-cyl RWD (Most efficient) 5.3L 8-cyl RWD 16 19 17 $3,840
15 Hybrid 5.3L 8-cyl 4WD 5.3L 8-cyl 4WD 15 18 16 $4,080

2005 GMC Sierra MPG

11–17 MPG, 9 MPGe · $3,840–$5,940/yr

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

Versus 2004: The most efficient configuration stays at 17 MPG. Its annual cost stays at $3,840.

Gas · 4.3L, 4.8L, 5.3L…
Combined
11–17 MPG
Per year
$3,840–$5,940
See gas configurations
Hybrid · 5.3L
Combined
16–17 MPG
Per year
$3,840–$4,080
See hybrid configurations
Natural gas · 6.0L
Combined
9 MPGe
Fuel cost
—

No fuel cost is shown for this fuel.

See natural gas configurations

Gas configurations (15)

2005 GMC Sierra gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
1500 4.8L 8-cyl RWD Automatic 4-spd (Most efficient) 4.8L 8-cyl RWD 15 19 17 $3,840
1500 4.3L 6-cyl RWD Automatic 4-spd 4.3L 6-cyl RWD 14 20 16 $4,080
1500 4.3L 6-cyl RWD Manual 5-spd 4.3L 6-cyl RWD 14 20 16 $4,080
1500 4.8L 8-cyl RWD Manual 5-spd 4.8L 8-cyl RWD 14 19 16 $4,080
1500 5.3L 8-cyl RWD Automatic 4-spd 5.3L 8-cyl RWD 14 19 16 $4,080
1500 4.8L 8-cyl 4WD Automatic 4-spd 4.8L 8-cyl 4WD 14 18 16 $4,080
Show 5 more configurations
2005 GMC Sierra gas configurations: EPA ratings and annual cost (+9)
TrimEngineDriveCityHwyComb.$/yr
1500 5.3L 8-cyl RWD Automatic 4-spd5.3L 8-cylRWD141916$4,080
1500 4.3L 6-cyl 4WD Automatic 4-spd4.3L 6-cyl4WD131715$4,360
1500 4.3L 6-cyl 4WD Manual 5-spd4.3L 6-cyl4WD131815$4,360
1500 4.8L 8-cyl 4WD Manual 5-spd4.8L 8-cyl4WD141815$4,360
1500 5.3L 8-cyl 4WD Automatic 4-spd5.3L 8-cyl4WD131715$4,360
1500 5.3L 8-cyl 4WD Automatic 4-spd5.3L 8-cyl4WD131715$4,360
1500 6.0L 8-cyl RWD6.0L 8-cylRWD131815$5,360
1500 6.0L 8-cyl 4WD6.0L 8-cyl4WD121513$5,030
2500 Hd6.0L 8-cylRWD101211$5,940

1 configuration requires or recommends higher-octane gasoline and is costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

Flex-fuel (E85) configurations are costed on gasoline, not E85.

Hybrid configurations (2)

2005 GMC Sierra hybrid configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
15 Hybrid 5.3L 8-cyl RWD (Most efficient) 5.3L 8-cyl RWD 16 19 17 $3,840
15 Hybrid 5.3L 8-cyl 4WD 5.3L 8-cyl 4WD 15 18 16 $4,080

Natural gas configurations (2)

2005 GMC Sierra natural gas configurations: EPA ratings and annual cost
TrimDriveCityHwyComb. MPGeRange
2500 HD CNG 6.0L 8-cyl RWD (Most efficient) RWD 8 11 9 —
2500 HD CNG 6.0L 8-cyl 4WD 4WD 8 11 9 —

No fuel cost is shown: there is no comparable official retail price series for natural gas.

2004 GMC Sierra MPG

13–17 MPG · $3,840–$5,030/yr

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

Versus 2003: The most efficient configuration moves from 16 to 17 MPG, up 1. Its annual cost goes from $4,080 to $3,840, $240 less.

Gas · 4.3L, 4.8L, 5.3L…
Combined
13–16 MPG
Per year
$4,080–$5,030
See gas configurations
Hybrid · 5.3L
Combined
16–17 MPG
Per year
$3,840–$4,080
See hybrid configurations

Gas configurations (14)

2004 GMC Sierra gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
1500 4.3L 6-cyl RWD Automatic 4-spd (Most efficient) 4.3L 6-cyl RWD 14 19 16 $4,080
1500 4.3L 6-cyl RWD Manual 5-spd 4.3L 6-cyl RWD 14 19 16 $4,080
1500 4.8L 8-cyl RWD Automatic 4-spd 4.8L 8-cyl RWD 15 19 16 $4,080
1500 4.8L 8-cyl RWD Manual 5-spd 4.8L 8-cyl RWD 14 19 16 $4,080
1500 5.3L 8-cyl RWD Automatic 4-spd 5.3L 8-cyl RWD 14 18 16 $4,080
1500 4.8L 8-cyl 4WD Automatic 4-spd 4.8L 8-cyl 4WD 13 17 15 $4,360
Show 4 more configurations
2004 GMC Sierra gas configurations: EPA ratings and annual cost (+8)
TrimEngineDriveCityHwyComb.$/yr
1500 5.3L 8-cyl 4WD Automatic 4-spd5.3L 8-cyl4WD131715$4,360
1500 5.3L 8-cyl RWD Automatic 4-spd5.3L 8-cylRWD131815$4,360
1500 6.0L 8-cyl RWD6.0L 8-cylRWD131614$4,670
1500 4.3L 6-cyl 4WD Automatic 4-spd4.3L 6-cyl4WD131714$4,670
1500 4.3L 6-cyl 4WD Manual 5-spd4.3L 6-cyl4WD131714$4,670
1500 4.8L 8-cyl 4WD Manual 5-spd4.8L 8-cyl4WD131614$4,670
1500 5.3L 8-cyl 4WD Automatic 4-spd5.3L 8-cyl4WD121614$4,670
1500 6.0L 8-cyl 4WD6.0L 8-cyl4WD121613$5,030

Flex-fuel (E85) configurations are costed on gasoline, not E85.

Hybrid configurations (2)

2004 GMC Sierra hybrid configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
15 Hybrid 5.3L 8-cyl RWD (Most efficient) 5.3L 8-cyl RWD 16 19 17 $3,840
15 Hybrid 5.3L 8-cyl 4WD 5.3L 8-cyl 4WD 15 17 16 $4,080

2003 GMC Sierra MPG

13–16 MPG · $4,080–$5,030/yr

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

Versus 2002: The most efficient configuration stays at 16 MPG. Its annual cost stays at $4,080.

Gas · 4.3L, 4.8L, 5.3L…
Combined
13–16 MPG
Per year
$4,080–$5,030

Gas configurations (13)

2003 GMC Sierra gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
1500 4.3L 6-cyl RWD Automatic 4-spd (Most efficient) 4.3L 6-cyl RWD 14 19 16 $4,080
1500 4.3L 6-cyl RWD Manual 5-spd 4.3L 6-cyl RWD 14 19 16 $4,080
1500 4.8L 8-cyl RWD Manual 5-spd 4.8L 8-cyl RWD 14 19 16 $4,080
1500 4.8L 8-cyl RWD Automatic 4-spd 4.8L 8-cyl RWD 14 18 15 $4,360
1500 5.3L 8-cyl RWD Automatic 4-spd 5.3L 8-cyl RWD 13 17 15 $4,360
1500 4.3L 6-cyl 4WD Automatic 4-spd 4.3L 6-cyl 4WD 13 17 15 $4,360
Show 3 more configurations
2003 GMC Sierra gas configurations: EPA ratings and annual cost (+7)
TrimEngineDriveCityHwyComb.$/yr
1500 5.3L 8-cyl RWD Automatic 4-spd5.3L 8-cylRWD131815$4,360
1500 4.3L 6-cyl 4WD Manual 5-spd4.3L 6-cyl4WD131714$4,670
1500 4.8L 8-cyl 4WD Automatic 4-spd4.8L 8-cyl4WD131614$4,670
1500 4.8L 8-cyl 4WD Manual 5-spd4.8L 8-cyl4WD131614$4,670
1500 5.3L 8-cyl 4WD Automatic 4-spd5.3L 8-cyl4WD131614$4,670
1500 5.3L 8-cyl 4WD Automatic 4-spd5.3L 8-cyl4WD121614$4,670
Denali 15006.0L 8-cyl4WD111513$5,030

Flex-fuel (E85) configurations are costed on gasoline, not E85.

2002 GMC Sierra MPG

12–16 MPG · $4,080–$5,440/yr

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

Versus 2001: The most efficient configuration moves from 17 to 16 MPG, down 1. Its annual cost goes from $3,840 to $4,080, $240 more.

Gas · 4.3L, 4.8L, 5.3L…
Combined
12–16 MPG
Per year
$4,080–$5,440

Gas configurations (12)

2002 GMC Sierra gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
1500 4.3L 6-cyl RWD Manual 5-spd (Most efficient) 4.3L 6-cyl RWD 15 19 16 $4,080
1500 4.3L 6-cyl RWD Automatic 4-spd 4.3L 6-cyl RWD 14 18 16 $4,080
1500 4.8L 8-cyl RWD Manual 5-spd 4.8L 8-cyl RWD 14 19 16 $4,080
1500 5.3L 8-cyl RWD 5.3L 8-cyl RWD 13 17 15 $4,360
1500 4.8L 8-cyl RWD Automatic 4-spd 4.8L 8-cyl RWD 14 18 15 $4,360
1500 4.3L 6-cyl 4WD Automatic 4-spd 4.3L 6-cyl 4WD 13 17 15 $4,360
Show 2 more configurations
2002 GMC Sierra gas configurations: EPA ratings and annual cost (+6)
TrimEngineDriveCityHwyComb.$/yr
1500 5.3L 8-cyl 4WD Automatic 4-spd5.3L 8-cyl4WD121614$4,670
1500 4.3L 6-cyl 4WD Manual 5-spd4.3L 6-cyl4WD131614$4,670
1500 4.8L 8-cyl 4WD Automatic 4-spd4.8L 8-cyl4WD131614$4,670
1500 4.8L 8-cyl 4WD Manual 5-spd4.8L 8-cyl4WD121614$4,670
1500 5.3L 8-cyl 4WD Automatic 4-spd5.3L 8-cyl4WD131614$4,670
Denali 15006.0L 8-cyl4WD111412$5,440

2001 GMC Sierra MPG

11–17 MPG · $3,840–$5,940/yr

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

Versus 2000: The most efficient configuration moves from 18 to 17 MPG, down 1. Its annual cost goes from $3,630 to $3,840, $210 more.

Gas · 4.3L, 4.8L, 5.3L…
Combined
11–17 MPG
Per year
$3,840–$5,940

Gas configurations (11)

2001 GMC Sierra gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
1500 4.3L 6-cyl RWD Automatic 4-spd (Most efficient) 4.3L 6-cyl RWD 15 20 17 $3,840
1500 4.3L 6-cyl RWD Manual 5-spd 4.3L 6-cyl RWD 14 18 16 $4,080
1500 4.8L 8-cyl RWD Automatic 4-spd 4.8L 8-cyl RWD 14 19 16 $4,080
1500 4.8L 8-cyl RWD Manual 5-spd 4.8L 8-cyl RWD 14 19 16 $4,080
1500 5.3L 8-cyl RWD 5.3L 8-cyl RWD 14 18 15 $4,360
1500 4.3L 6-cyl 4WD Automatic 4-spd 4.3L 6-cyl 4WD 14 18 15 $4,360
Show 1 more configuration
2001 GMC Sierra gas configurations: EPA ratings and annual cost (+5)
TrimEngineDriveCityHwyComb.$/yr
1500 4.3L 6-cyl 4WD Manual 5-spd4.3L 6-cyl4WD131614$4,670
1500 4.8L 8-cyl 4WD Automatic 4-spd4.8L 8-cyl4WD131614$4,670
1500 4.8L 8-cyl 4WD Manual 5-spd4.8L 8-cyl4WD131614$4,670
1500 5.3L 8-cyl 4WD5.3L 8-cyl4WD131614$4,670
1500 6.0L 8-cyl6.0L 8-cyl4WD101311$5,940

2000 GMC Sierra MPG

12–18 MPG · $3,630–$5,440/yr

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

Gas · 4.3L, 4.8L, 5.3L…
Combined
12–18 MPG
Per year
$3,630–$5,440

Gas configurations (12)

2000 GMC Sierra gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
1500 4.3L 6-cyl RWD Manual 5-spd (Most efficient) 4.3L 6-cyl RWD 15 21 18 $3,630
1500 4.3L 6-cyl RWD Automatic 4-spd 4.3L 6-cyl RWD 15 19 16 $4,080
1500 4.8L 8-cyl RWD Automatic 4-spd 4.8L 8-cyl RWD 14 19 16 $4,080
1500 4.8L 8-cyl RWD Manual 5-spd 4.8L 8-cyl RWD 14 19 16 $4,080
1500 5.3L 8-cyl RWD 5.3L 8-cyl RWD 14 19 16 $4,080
1500 4.3L 6-cyl 4WD Automatic 4-spd 4.3L 6-cyl 4WD 14 18 16 $4,080
Show 2 more configurations
2000 GMC Sierra gas configurations: EPA ratings and annual cost (+6)
TrimEngineDriveCityHwyComb.$/yr
2500 5.3L 8-cyl5.3L 8-cylRWD141815$4,360
1500 4.3L 6-cyl 4WD Manual 5-spd4.3L 6-cyl4WD131615$4,360
1500 4.8L 8-cyl 4WD Automatic 4-spd4.8L 8-cyl4WD141715$4,360
1500 4.8L 8-cyl 4WD Manual 5-spd4.8L 8-cyl4WD131815$4,360
1500 5.3L 8-cyl 4WD5.3L 8-cyl4WD131614$4,670
2500 6.0L 8-cyl6.0L 8-cylRWD111512$5,440

Fuel cost by state

Yearly cost of the 1500 4.3L 6-cyl RWD: $5,230 in California and $3,350 in Texas, a $1,880 difference.

Gasoline prices: California: California state average; Washington: Washington state average; New York: New York state average; Florida: Florida state average; Texas: Texas state average (Sep 2026).
Fuel cost in every state

Similar cars

Closest combined MPG among MY2006 standard pickup models.

1998 Chevrolet Silverado 1500

2006 Chevrolet Silverado

17 MPG · $3,840/yr
2007 Honda Ridgeline RTL (YK1)

2006 Honda Ridgeline

17 MPG · $3,840/yr
2007 Dodge Dakota ST

2006 Dodge Dakota Pickup

17 MPG · $3,840/yr
2006 Mitsubishi Raider Double Cab XLS V8

2006 Mitsubishi Raider Pickup

17 MPG · $3,840/yr
EPA ratings: fueleconomy.gov file of Sep 29, 2026 · Prices: EIA regular gasoline, U.S. average, Sep 2026 ($4.36/gal) · 15,000 mi/yr, 55% city / 45% highway · How we calculate

Generations

All GMC Sierra years All GMC models

Frequently asked questions

What gas mileage does the 2000-2006 GMC Sierra get?

EPA rates the 2000-2006 GMC Sierra at 11–18 MPG combined across 100 configurations and 7 model years. The most efficient version, the 2000 1500 4.3L 6-cyl RWD, is rated 18 MPG (15 city, 21 highway). By powertrain: Gas: 11–18 MPG; Hybrid: 16–17 MPG; Natural gas: 9 MPGe.

Which years had the best MPG in the 2000-2006 GMC Sierra?

The 1500 4.3L 6-cyl RWD reached the generation's best combined rating, 18 MPG, in 2000. The lowest top rating, 16 MPG, was in 2002 and 2003.

Did EPA ratings change during the 2000-2006 GMC Sierra?

Yes. Ratings changed in 2001, 2002, 2003, 2004, 2005 and 2006.

How much does it cost to fuel a 2006 GMC Sierra per year?

Driving 15,000 miles a year at regular gasoline $4.36/gal (U.S. average, Sep 2026), the 1500 4.3L 6-cyl RWD costs about $3,840 a year. Across all 17 configurations the cost runs $3,840–$6,180 a year. That is a $2,340 difference between the cheapest and the costliest configuration.

How much does it cost to drive a 2006 GMC Sierra 100 miles?

About $25.60 per 100 miles for the 1500 4.3L 6-cyl RWD at regular gasoline $4.36/gal (U.S. average, Sep 2026), and between $25.60 and $41.20 across all configurations. That is the annual cost over 15,000 miles divided by 150.

Is the 2006 GMC Sierra more efficient in the city or on the highway?

The 1500 4.3L 6-cyl RWD is rated 15 city and 20 highway MPG, so it is more efficient on the highway, by 5 MPG.

How does the 2006 GMC Sierra compare with other standard pickup configurations?

The 1500 4.3L 6-cyl RWD costs about $3,840 a year to fuel, $240 less than the class median of $4,080, and less than 6 of 10 standard pickup configurations. The comparison covers all 155 rated standard pickup configurations for MY2006, not weighted by sales.

Is the 2006 GMC Sierra hybrid cheaper to fuel than the gas version?

About the same. The best hybrid (15 Hybrid 5.3L 8-cyl RWD) is rated 17 MPG against 17 MPG for the best gas version (1500 4.3L 6-cyl RWD), and both cost $3,840 a year at regular gasoline $4.36/gal (U.S. average, Sep 2026).

Is the 2006 GMC Sierra different from the 2005 model?

The most efficient configuration stays at 17 MPG. Its annual cost stays at $3,840. EPA lists 17 configurations for 2006 against 19 configurations for 2005. See the 2005 GMC Sierra for that year.