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Mercedes-Benz E 400 e 4MATIC Auto Zuerich 2023 1X7A0936 (W214)
Shown: Mercedes-Benz E 400 e 4MATIC Auto Zuerich 2023 1X7A0936 (W214). Photo: Alexander-93, CC BY-SA 4.0, via Wikimedia Commons
  • Newest year: 2027
  • Hybrid
  • Midsize cars
  • Partial model year

2024-2027 Mercedes-Benz E-Class MPG & Fuel Cost

4 model years · 25–28 MPG combined

28 MPG
Combined
25 MPG
City
33 MPG
Highway
Annual fuel cost · E350 2.0L 4-cyl turbo RWD
$2,880

15,000 mi/yr · premium gasoline $5.36/gal (U.S. average, Sep 2026)

Cheaper to fuel than 2 of 10 midsize car configurations, MY2027. Ranked against all rated configurations, not sales-weighted.

2024-2027 Mercedes-Benz E-Class at a glance

The 2024-2027 Mercedes-Benz E-Class covers 4 model years in the EPA database (18 configurations in all), rated 25–28 MPG combined. The newest model year, 2027, costs about $2,880 a year to fuel for its most efficient version, the E350 2.0L 4-cyl turbo RWD (28 MPG), at premium gasoline $5.36/gal (U.S. average, Sep 2026). Powertrains over the years: hybrid and plug-in hybrid. EPA changed the ratings in 2025, 2026 and 2027. The best combined rating in the generation, 28 MPG, was reached in 2025, 2026 and 2027.

Model year 2027 is still being filled in by EPA (4 configurations listed so far), so rows may be added.

2024-2027 Mercedes-Benz E-Class by model year

2024-2027 Mercedes-Benz E-Class: EPA combined rating and yearly fuel cost for each model year
Model yearPowertrainsCombined$/yrEPA ratings
2027 (partial) Hybrid 25–28 MPG $2,880–$3,210 Ratings changed
2026 Hybrid, Plug-in hybrid 25–28 MPG $2,090–$3,210 Ratings changed
2025 Hybrid, Plug-in hybrid 25–28 MPG $2,140–$3,210 Ratings changed
2024 Hybrid 25–27 MPG $2,950–$3,210 First year

What the 2027 E350 2.0L 4-cyl turbo RWD costs to drive

Per month

$240

$2,880 a year ÷ 12

Per 25 miles

$4.80

Per 100 miles

$19.20

Five years

$14,400

5 × the yearly cost, prices held at today's level

vs the midsize car median

$650more a year

Class median $2,230 a year, MY2027

Based on 15,000 miles a year and premium gasoline $5.36/gal (U.S. average, Sep 2026).

2027 Mercedes-Benz E-Class MPG

Model year 2027 is still being filled in by EPA (4 configurations listed so far), so rows may be added.

Versus 2026: The most efficient configuration stays at 28 MPG. Its annual cost stays at $2,880.

Hybrid · 2.0L, 3.0L
Combined
25–28 MPG
Per year
$2,880–$3,210

Hybrid configurations (4)

2027 Mercedes-Benz E-Class hybrid configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
E350 (Most efficient) 2.0L 4-cyl turbo RWD 25 33 28 $2,880
E350 4matic 2.0L 4-cyl turbo AWD 24 33 27 $2,980
E450 4matic All-Terrain (wagon) 3.0L 6-cyl turbo supercharged AWD 22 31 25 $3,170
E450 4matic 3.0L 6-cyl turbo supercharged AWD 22 31 25 $3,210

4 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2026 Mercedes-Benz E-Class MPG

25–28 MPG · $2,090–$3,210/yr

Versus 2025: The most efficient configuration stays at 28 MPG. Its annual cost stays at $2,880.

Hybrid · 2.0L, 3.0L
Combined
25–28 MPG
Per year
$2,880–$3,210
See hybrid configurations
Plug-in hybrid · 3.0L
Gas-only combined
22–24 MPG
Per year
$2,090–$2,230

On electricity 56–60 MPGe, with 41–44 miles of electric range.

See plug-in hybrid configurations

Hybrid configurations (4)

2026 Mercedes-Benz E-Class hybrid configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
E350 (Most efficient) 2.0L 4-cyl turbo RWD 25 33 28 $2,880
E350 4matic 2.0L 4-cyl turbo AWD 24 33 27 $2,980
E450 4matic All-Terrain (wagon) 3.0L 6-cyl turbo supercharged AWD 22 31 25 $3,170
E450 4matic 3.0L 6-cyl turbo supercharged AWD 22 31 25 $3,210

4 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

Plug-in hybrid configurations (2)

2026 Mercedes-Benz E-Class plug-in hybrid configurations: EPA ratings and annual cost
TrimDriveGas MPGElectric MPGeElectric range$/yr
AMG E53 Hybrid 4matic Plus (Most efficient) AWD 24 60 44 mi $2,090
AMG E53 Hybrid 4matic Plus (station wagon) AWD 22 56 41 mi $2,230

Cost assumes EPA's utility factor: 69%–71% of miles are driven on electricity (residential electricity 18.3¢/kWh (U.S. average, Jul 2026)) and the rest on gasoline (premium gasoline $5.36/gal (U.S. average, Sep 2026)).

2025 Mercedes-Benz E-Class MPG

25–28 MPG · $2,140–$3,210/yr

Versus 2024: The most efficient configuration moves from 27 to 28 MPG, up 1. Its annual cost goes from $2,950 to $2,880, $70 less.

Hybrid · 2.0L, 3.0L
Combined
25–28 MPG
Per year
$2,880–$3,210
See hybrid configurations
Plug-in hybrid · 3.0L
Gas-only combined
23 MPG
Per year
$2,140

On electricity 59 MPGe, with 43 miles of electric range.

See plug-in hybrid configurations

Hybrid configurations (4)

2025 Mercedes-Benz E-Class hybrid configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
E350 (Most efficient) 2.0L 4-cyl turbo RWD 25 33 28 $2,880
E350 4matic 2.0L 4-cyl turbo AWD 24 33 27 $2,980
E450 4matic All-Terrain (wagon) 3.0L 6-cyl turbo supercharged AWD 22 31 25 $3,170
E450 4matic 3.0L 6-cyl turbo supercharged AWD 22 31 25 $3,210

4 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

Plug-in hybrid configurations (1)

2025 Mercedes-Benz E-Class plug-in hybrid configurations: EPA ratings and annual cost
TrimDriveGas MPGElectric MPGeElectric range$/yr
AMG E53 Hybrid 4matic Plus (Most efficient) AWD 23 59 43 mi $2,140

Cost assumes EPA's utility factor: 70% of miles are driven on electricity (residential electricity 18.3¢/kWh (U.S. average, Jul 2026)) and the rest on gasoline (premium gasoline $5.36/gal (U.S. average, Sep 2026)).

2024 Mercedes-Benz E-Class MPG

25–27 MPG · $2,950–$3,210/yr
Hybrid · 2.0L, 3.0L
Combined
25–27 MPG
Per year
$2,950–$3,210

Hybrid configurations (3)

2024 Mercedes-Benz E-Class hybrid configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
E350 4matic (Most efficient) 2.0L 4-cyl turbo AWD 24 33 27 $2,950
E450 4matic All-Terrain (wagon) 3.0L 6-cyl turbo supercharged AWD 22 31 25 $3,170
E450 4matic 3.0L 6-cyl turbo supercharged AWD 22 31 25 $3,210

3 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

Fuel cost by state

Yearly cost of the E350 2.0L 4-cyl turbo RWD: $3,430 in California and $2,500 in Texas, a $930 difference.

Gasoline prices: California: California state average; Washington: Washington state average; New York: New York state average; Florida: Florida state average; Texas: Texas state average (Sep 2026).
Fuel cost in every state

Similar cars

Closest combined MPG among MY2027 midsize car models.

EPA ratings: fueleconomy.gov file of Sep 29, 2026 · Prices: EIA regular gasoline, U.S. average, Sep 2026 ($4.36/gal) · 15,000 mi/yr, 55% city / 45% highway · How we calculate

Generations

Frequently asked questions

What gas mileage does the 2024-2027 Mercedes-Benz E-Class get?

EPA rates the 2024-2027 Mercedes-Benz E-Class at 25–28 MPG combined across 18 configurations and 4 model years. The most efficient version, the 2027 E350 2.0L 4-cyl turbo RWD, is rated 28 MPG (25 city, 33 highway). By powertrain: Hybrid: 25–28 MPG; Plug-in hybrid: 22–24 MPG.

Which years had the best MPG in the 2024-2027 Mercedes-Benz E-Class?

The E350 2.0L 4-cyl turbo RWD reached the generation's best combined rating, 28 MPG, in 2025, 2026 and 2027. The lowest top rating, 27 MPG, was in 2024.

Did EPA ratings change during the 2024-2027 Mercedes-Benz E-Class?

Yes. Ratings changed in 2025, 2026 and 2027.

How does the 2024-2027 Mercedes-Benz E-Class compare with the previous generation?

The previous generation (2017-2023 Mercedes-Benz E-Class) is rated 18–26 MPG combined and costs $3,060–$4,590 a year to fuel; the 2024-2027 model is rated 25–28 MPG and costs $2,090–$3,210 a year.

How much does it cost to fuel a 2027 Mercedes-Benz E-Class per year?

Driving 15,000 miles a year at premium gasoline $5.36/gal (U.S. average, Sep 2026), the E350 2.0L 4-cyl turbo RWD costs about $2,880 a year. Across all 4 configurations the cost runs $2,880–$3,210 a year. That is a $330 difference between the cheapest and the costliest configuration.

How much does it cost to drive a 2027 Mercedes-Benz E-Class 100 miles?

About $19.20 per 100 miles for the E350 2.0L 4-cyl turbo RWD at premium gasoline $5.36/gal (U.S. average, Sep 2026), and between $19.20 and $21.40 across all configurations. That is the annual cost over 15,000 miles divided by 150.

Is the 2027 Mercedes-Benz E-Class more efficient in the city or on the highway?

The E350 2.0L 4-cyl turbo RWD is rated 25 city and 33 highway MPG, so it is more efficient on the highway, by 8 MPG.

How does the 2027 Mercedes-Benz E-Class compare with other midsize car configurations?

The E350 2.0L 4-cyl turbo RWD costs about $2,880 a year to fuel, $650 more than the class median of $2,230, and less than 2 of 10 midsize car configurations. The comparison covers all 26 rated midsize car configurations for MY2027, not weighted by sales.

Is the 2027 Mercedes-Benz E-Class different from the 2026 model?

The most efficient configuration stays at 28 MPG. Its annual cost stays at $2,880. EPA lists 4 configurations for 2027 against 6 configurations for 2026. See the 2026 Mercedes-Benz E-Class for that year.