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Mercedes-Benz ML 350 CDI 4MATIC Grand Edition (W 164 (W166)
Shown: Mercedes-Benz ML 350 CDI 4MATIC Grand Edition (W 164 (W166). Photo: M 93, CC BY-SA 3.0 DE, via Wikimedia Commons
  • Newest year: 2015
  • Gas
  • Diesel
  • Standard SUVs

2012-2015 Mercedes-Benz ML-Class MPG & Fuel Cost

4 model years · 15–25 MPG combined

20 MPG
Combined
18 MPG
City
23 MPG
Highway
Annual fuel cost · ML350 3.5L 6-cyl RWD
$3,970

15,000 mi/yr · premium gasoline $5.36/gal (U.S. average, Sep 2026)

Cheaper to fuel than 4 of 10 standard SUV configurations, MY2015. Ranked against all rated configurations, not sales-weighted.

2012-2015 Mercedes-Benz ML-Class at a glance

The 2012-2015 Mercedes-Benz ML-Class covers 4 model years in the EPA database (20 configurations in all), rated 15–25 MPG combined. The newest model year, 2015, costs about $3,830 a year to fuel for its most efficient version, the ML250 Bluetec 4matic 2.1L 4-cyl turbo 4WD (25 MPG), at diesel $6.29/gal (U.S. average, Sep 2026). Powertrains over the years: gas and diesel. EPA changed the ratings in 2013, 2014 and 2015. The best combined rating in the generation, 25 MPG, was reached in 2015.

2012-2015 Mercedes-Benz ML-Class by model year

2012-2015 Mercedes-Benz ML-Class: EPA combined rating and yearly fuel cost for each model year
Model yearPowertrainsCombined$/yrEPA ratings
2015 Gas, Diesel 15–25 MPG $3,830–$5,530 Ratings changed
2014 Gas 15–20 MPG $3,970–$5,530 Ratings changed
2013 Gas 15–20 MPG $4,010–$5,530 Ratings changed
2012 Gas 15–20 MPG $4,080–$5,200 First year

What the 2015 ML350 3.5L 6-cyl RWD costs to drive

Per month

$331

$3,970 a year ÷ 12

Per 25 miles

$6.62

Per 100 miles

$26.47

Five years

$19,850

5 × the yearly cost, prices held at today's level

vs the standard SUV median

$170more a year

Class median $3,800 a year, MY2015

Based on 15,000 miles a year and premium gasoline $5.36/gal (U.S. average, Sep 2026).

2015 Mercedes-Benz ML-Class MPG

Versus 2014: The most efficient configuration moves from 20 to 25 MPG, up 5. Its annual cost goes from $3,970 to $3,830, $140 less.

Gas · 3.0L, 3.5L, 5.5L
Combined
15–20 MPG
Per year
$3,970–$5,530
See gas configurations
Diesel · 2.1L
Combined
25 MPG
Per year
$3,830
See diesel configurations

Gas configurations (5)

2015 Mercedes-Benz ML-Class gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
ML350 (Most efficient) 3.5L 6-cyl RWD 18 23 20 $3,970
ML400 4matic 3.0L 6-cyl turbo 4WD 18 22 20 $4,110
ML350 4matic 3.5L 6-cyl 4WD Automatic 7-spd 3.5L 6-cyl 4WD 18 22 19 $4,140
ML350 4matic 3.5L 6-cyl 4WD Automatic 7-spd 3.5L 6-cyl 4WD 18 22 19 $4,140
ML63 AMG 5.5L 8-cyl turbo 4WD 13 17 15 $5,530

5 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

Flex-fuel (E85) configurations are costed on gasoline, not E85.

Diesel configurations (1)

2015 Mercedes-Benz ML-Class diesel configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
ML250 Bluetec 4matic (Most efficient) 2.1L 4-cyl turbo 4WD 22 29 25 $3,830

Diesel is priced at diesel $6.29/gal (U.S. average, Sep 2026).

2014 Mercedes-Benz ML-Class MPG

15–20 MPG · $3,970–$5,530/yr

Versus 2013: The most efficient configuration stays at 20 MPG. Its annual cost goes from $4,010 to $3,970, $40 less.

Gas · 3.5L, 4.7L, 5.5L
Combined
15–20 MPG
Per year
$3,970–$5,530

Gas configurations (5)

2014 Mercedes-Benz ML-Class gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
ML350 (Most efficient) 3.5L 6-cyl RWD 18 23 20 $3,970
ML350 4matic 3.5L 6-cyl 4WD Automatic 7-spd 3.5L 6-cyl 4WD 18 22 19 $4,140
ML350 4matic 3.5L 6-cyl 4WD Automatic 7-spd 3.5L 6-cyl 4WD 18 22 19 $4,140
ML550 4matic 4.7L 8-cyl turbo 4WD 14 19 16 $4,990
ML63 AMG 5.5L 8-cyl turbo 4WD 13 17 15 $5,530

5 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

Flex-fuel (E85) configurations are costed on gasoline, not E85.

2013 Mercedes-Benz ML-Class MPG

15–20 MPG · $4,010–$5,530/yr

Versus 2012: The most efficient configuration stays at 20 MPG. Its annual cost goes from $4,080 to $4,010, $70 less.

Gas · 3.5L, 4.7L, 5.5L
Combined
15–20 MPG
Per year
$4,010–$5,530

Gas configurations (5)

2013 Mercedes-Benz ML-Class gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
ML350 (Most efficient) 3.5L 6-cyl RWD 18 23 20 $4,010
ML350 4matic 3.5L 6-cyl 4WD Automatic 7-spd 3.5L 6-cyl 4WD 18 23 20 $4,080
ML350 4matic 3.5L 6-cyl 4WD Automatic 7-spd 3.5L 6-cyl 4WD 18 23 20 $4,080
ML550 4matic 4.7L 8-cyl turbo 4WD 14 20 16 $4,900
ML63 AMG 5.5L 8-cyl turbo 4WD 13 17 15 $5,530

5 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

Flex-fuel (E85) configurations are costed on gasoline, not E85.

2012 Mercedes-Benz ML-Class MPG

15–20 MPG · $4,080–$5,200/yr
Gas · 3.5L, 4.7L, 5.5L
Combined
15–20 MPG
Per year
$4,080–$5,200

Gas configurations (4)

2012 Mercedes-Benz ML-Class gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
ML350 4matic 3.5L 6-cyl 4WD Automatic 7-spd (Most efficient) 3.5L 6-cyl 4WD 18 23 20 $4,080
ML350 4matic 3.5L 6-cyl 4WD Automatic 7-spd 3.5L 6-cyl 4WD 17 22 19 $4,220
ML550 4matic 4.7L 8-cyl turbo 4WD 15 20 17 $4,800
ML63 AMG 5.5L 8-cyl turbo 4WD 14 18 15 $5,200

4 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

Flex-fuel (E85) configurations are costed on gasoline, not E85.

Fuel cost by state

Yearly cost of the ML350 3.5L 6-cyl RWD: $4,740 in California and $3,440 in Texas, a $1,300 difference.

Gasoline prices: California: California state average; Washington: Washington state average; New York: New York state average; Florida: Florida state average; Texas: Texas state average (Sep 2026).
Fuel cost in every state

Similar cars

Closest combined MPG among MY2015 standard SUV models.

EPA ratings: fueleconomy.gov file of Sep 29, 2026 · Prices: EIA regular gasoline, U.S. average, Sep 2026 ($4.36/gal) · 15,000 mi/yr, 55% city / 45% highway · How we calculate

Generations

Frequently asked questions

What gas mileage does the 2012-2015 Mercedes-Benz ML-Class get?

EPA rates the 2012-2015 Mercedes-Benz ML-Class at 15–25 MPG combined across 20 configurations and 4 model years. The most efficient version, the 2015 ML250 Bluetec 4matic 2.1L 4-cyl turbo 4WD, is rated 25 MPG (22 city, 29 highway). By powertrain: Gas: 15–20 MPG; Diesel: 25 MPG.

Which years had the best MPG in the 2012-2015 Mercedes-Benz ML-Class?

The ML250 Bluetec 4matic 2.1L 4-cyl turbo 4WD reached the generation's best combined rating, 25 MPG, in 2015. The lowest top rating, 20 MPG, was in 2012, 2013 and 2014.

Did EPA ratings change during the 2012-2015 Mercedes-Benz ML-Class?

Yes. Ratings changed in 2013, 2014 and 2015.

How does the 2012-2015 Mercedes-Benz ML-Class compare with the previous generation?

The previous generation (2006-2011 Mercedes-Benz ML-Class) is rated 12–22 MPG combined and costs $3,650–$6,700 a year to fuel; the 2012-2015 model is rated 15–25 MPG and costs $3,830–$5,530 a year.

How much does it cost to fuel a 2015 Mercedes-Benz ML-Class per year?

Driving 15,000 miles a year at premium gasoline $5.36/gal (U.S. average, Sep 2026), the ML350 3.5L 6-cyl RWD costs about $3,970 a year. Across all 6 configurations the cost runs $3,830–$5,530 a year. That is a $1,700 difference between the cheapest and the costliest configuration.

How much does it cost to drive a 2015 Mercedes-Benz ML-Class 100 miles?

About $26.47 per 100 miles for the ML350 3.5L 6-cyl RWD at premium gasoline $5.36/gal (U.S. average, Sep 2026), and between $25.53 and $36.87 across all configurations. That is the annual cost over 15,000 miles divided by 150.

Is the 2015 Mercedes-Benz ML-Class more efficient in the city or on the highway?

The ML350 3.5L 6-cyl RWD is rated 18 city and 23 highway MPG, so it is more efficient on the highway, by 5 MPG.

How does the 2015 Mercedes-Benz ML-Class compare with other standard SUV configurations?

The ML350 3.5L 6-cyl RWD costs about $3,970 a year to fuel, $170 more than the class median of $3,800, and less than 4 of 10 standard SUV configurations. The comparison covers all 134 rated standard SUV configurations for MY2015, not weighted by sales.

Is the 2015 Mercedes-Benz ML-Class different from the 2014 model?

The most efficient configuration moves from 20 to 25 MPG, up 5. Its annual cost goes from $3,970 to $3,830, $140 less. EPA lists 6 configurations for 2015 against 5 configurations for 2014. See the 2014 Mercedes-Benz ML-Class for that year.