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Mercedes-Benz ML-Class (W164)
Photo shows the 2006 model (next generation): Mercedes-Benz ML-Class (W164). Photo: M 93, CC BY-SA 3.0, via Wikimedia Commons
  • Newest year: 2005
  • Gas
  • Standard SUVs
  • Same as 2004

2000-2005 Mercedes-Benz ML-Class MPG & Fuel Cost

6 model years · 14–17 MPG combined

15 MPG
Combined
14 MPG
City
17 MPG
Highway
Annual fuel cost · ML350 3.7L 6-cyl 4WD
$5,360

15,000 mi/yr · premium gasoline $5.36/gal (U.S. average, Sep 2026)

Cheaper to fuel than 1 of 10 standard SUV configurations, MY2005. Ranked against all rated configurations, not sales-weighted.

2000-2005 Mercedes-Benz ML-Class at a glance

The 2000-2005 Mercedes-Benz ML-Class covers 6 model years in the EPA database (17 configurations in all), rated 14–17 MPG combined. The newest model year, 2005, costs about $5,360 a year to fuel for its most efficient version, the ML350 3.7L 6-cyl 4WD (15 MPG), at premium gasoline $5.36/gal (U.S. average, Sep 2026). EPA changed the ratings in 2001, 2002, 2003 and 2004; 2005 repeat the values of the year before. The best combined rating in the generation, 17 MPG, was reached in 2001.

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

2000-2005 Mercedes-Benz ML-Class by model year

2000-2005 Mercedes-Benz ML-Class: EPA combined rating and yearly fuel cost for each model year
Model yearPowertrainsCombined$/yrEPA ratings
2005 Gas 14–15 MPG $5,360–$5,740 Same EPA ratings as 2004
2004 Gas 14–15 MPG $5,360–$5,740 Ratings changed
2003 Gas 14–15 MPG $5,360–$5,740 Ratings changed
2002 Gas 14–15 MPG $5,360–$5,740 Ratings changed
2001 Gas 14–17 MPG $4,730–$5,740 Ratings changed
2000 Gas 14–16 MPG $5,020–$5,740 First year

What the 2005 ML350 3.7L 6-cyl 4WD costs to drive

Per month

$447

$5,360 a year ÷ 12

Per 25 miles

$8.93

Per 100 miles

$35.73

Five years

$26,800

5 × the yearly cost, prices held at today's level

vs the standard SUV median

$1,280more a year

Class median $4,080 a year, MY2005

Based on 15,000 miles a year and premium gasoline $5.36/gal (U.S. average, Sep 2026).

2005 Mercedes-Benz ML-Class MPG

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

EPA lists the same ratings for the 2005 Mercedes-Benz ML-Class as for the 2004 model, so the configurations and costs are the ones in the 2004 section above.See 2004

Gas · 3.7L, 5.0L
Combined
14–15 MPG
Per year
$5,360–$5,740

Gas configurations (2)

2005 Mercedes-Benz ML-Class gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
ML350 (Most efficient) 3.7L 6-cyl 4WD 14 17 15 $5,360
ML500 5.0L 8-cyl 4WD 13 16 14 $5,740

2 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2004 Mercedes-Benz ML-Class MPG

14–15 MPG · $5,360–$5,740/yr

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

Versus 2003: The most efficient configuration stays at 15 MPG. Its annual cost stays at $5,360.

Gas · 3.7L, 5.0L
Combined
14–15 MPG
Per year
$5,360–$5,740

Gas configurations (2)

2004 Mercedes-Benz ML-Class gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
ML350 (Most efficient) 3.7L 6-cyl 4WD 14 17 15 $5,360
ML500 5.0L 8-cyl 4WD 13 16 14 $5,740

2 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2003 Mercedes-Benz ML-Class MPG

14–15 MPG · $5,360–$5,740/yr

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

Versus 2002: The most efficient configuration stays at 15 MPG. Its annual cost stays at $5,360.

Gas · 3.2L, 3.7L, 5.0L…
Combined
14–15 MPG
Per year
$5,360–$5,740

Gas configurations (4)

2003 Mercedes-Benz ML-Class gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
ML320 (Most efficient) 3.2L 6-cyl 4WD 14 17 15 $5,360
ML350 3.7L 6-cyl 4WD 14 17 15 $5,360
ML500 5.0L 8-cyl 4WD 13 16 14 $5,740
ML55 AMG 5.5L 8-cyl 4WD 13 17 14 $5,740

4 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2002 Mercedes-Benz ML-Class MPG

14–15 MPG · $5,360–$5,740/yr

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

Versus 2001: The most efficient configuration moves from 17 to 15 MPG, down 2. Its annual cost goes from $4,730 to $5,360, $630 more.

Gas · 3.2L, 5.0L, 5.5L
Combined
14–15 MPG
Per year
$5,360–$5,740

Gas configurations (3)

2002 Mercedes-Benz ML-Class gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
ML320 (Most efficient) 3.2L 6-cyl 4WD 14 17 15 $5,360
ML500 5.0L 8-cyl 4WD 13 16 14 $5,740
ML55 AMG 5.5L 8-cyl 4WD 12 16 14 $5,740

3 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2001 Mercedes-Benz ML-Class MPG

14–17 MPG · $4,730–$5,740/yr

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

Versus 2000: The most efficient configuration moves from 16 to 17 MPG, up 1. Its annual cost goes from $5,020 to $4,730, $290 less.

Gas · 3.2L, 4.3L, 5.5L
Combined
14–17 MPG
Per year
$4,730–$5,740

Gas configurations (3)

2001 Mercedes-Benz ML-Class gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
ML320 (Most efficient) 3.2L 6-cyl 4WD 15 19 17 $4,730
ML430 4.3L 8-cyl 4WD 14 19 16 $5,020
ML55 AMG 5.5L 8-cyl 4WD 12 16 14 $5,740

3 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2000 Mercedes-Benz ML-Class MPG

14–16 MPG · $5,020–$5,740/yr

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

Gas · 3.2L, 4.3L, 5.5L
Combined
14–16 MPG
Per year
$5,020–$5,740

Gas configurations (3)

2000 Mercedes-Benz ML-Class gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
ML320 (Most efficient) 3.2L 6-cyl 4WD 15 18 16 $5,020
ML430 4.3L 8-cyl 4WD 14 17 15 $5,360
ML55 5.5L 8-cyl 4WD 12 16 14 $5,740

3 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

Fuel cost by state

Yearly cost of the ML350 3.7L 6-cyl 4WD: $6,390 in California and $4,650 in Texas, a $1,740 difference.

Gasoline prices: California: California state average; Washington: Washington state average; New York: New York state average; Florida: Florida state average; Texas: Texas state average (Sep 2026).
Fuel cost in every state

Similar cars

Closest combined MPG among MY2005 standard SUV models.

EPA ratings: fueleconomy.gov file of Sep 29, 2026 · Prices: EIA regular gasoline, U.S. average, Sep 2026 ($4.36/gal) · 15,000 mi/yr, 55% city / 45% highway · How we calculate

Generations

Frequently asked questions

What gas mileage does the 2000-2005 Mercedes-Benz ML-Class get?

EPA rates the 2000-2005 Mercedes-Benz ML-Class at 14–17 MPG combined across 17 configurations and 6 model years. The most efficient version, the 2001 ML320 3.2L 6-cyl 4WD, is rated 17 MPG (15 city, 19 highway).

Which years had the best MPG in the 2000-2005 Mercedes-Benz ML-Class?

The ML320 3.2L 6-cyl 4WD reached the generation's best combined rating, 17 MPG, in 2001. The lowest top rating, 15 MPG, was in 2002, 2003, 2004 and 2005.

Did EPA ratings change during the 2000-2005 Mercedes-Benz ML-Class?

Yes. Ratings changed in 2001, 2002, 2003 and 2004. In 2005 the values repeat the year before.

How much does it cost to fuel a 2005 Mercedes-Benz ML-Class per year?

Driving 15,000 miles a year at premium gasoline $5.36/gal (U.S. average, Sep 2026), the ML350 3.7L 6-cyl 4WD costs about $5,360 a year. Across all 2 configurations the cost runs $5,360–$5,740 a year. That is a $380 difference between the cheapest and the costliest configuration.

How much does it cost to drive a 2005 Mercedes-Benz ML-Class 100 miles?

About $35.73 per 100 miles for the ML350 3.7L 6-cyl 4WD at premium gasoline $5.36/gal (U.S. average, Sep 2026), and between $35.73 and $38.27 across all configurations. That is the annual cost over 15,000 miles divided by 150.

Is the 2005 Mercedes-Benz ML-Class more efficient in the city or on the highway?

The ML350 3.7L 6-cyl 4WD is rated 14 city and 17 highway MPG, so it is more efficient on the highway, by 3 MPG.

How does the 2005 Mercedes-Benz ML-Class compare with other standard SUV configurations?

The ML350 3.7L 6-cyl 4WD costs about $5,360 a year to fuel, $1,280 more than the class median of $4,080, and less than 1 of 10 standard SUV configurations. The comparison covers all 287 rated standard SUV configurations for MY2005, not weighted by sales.

Is the 2005 Mercedes-Benz ML-Class different from the 2004 model?

No. EPA lists the same ratings for 2004 and 2005: 2 configurations rated 14–15 MPG combined. See the 2004 Mercedes-Benz ML-Class for that year.