- Newest year: 2011
- Gas
- Hybrid
- Standard SUVs
2006-2011 Mercedes-Benz ML-Class MPG & Fuel Cost
6 model years · 12–22 MPG combined
15,000 mi/yr · premium gasoline $5.36/gal (U.S. average, Sep 2026)
Cheaper to fuel than 1 of 10 standard SUV configurations, MY2011. Ranked against all rated configurations, not sales-weighted.
2006-2011 Mercedes-Benz ML-Class at a glance
The 2006-2011 Mercedes-Benz ML-Class covers 6 model years in the EPA database (24 configurations in all), rated 12–22 MPG combined. The newest model year, 2011, costs about $3,680 a year to fuel for its most efficient version, the ML450 Hybrid 4matic 3.5L 6-cyl 4WD (22 MPG), at premium gasoline $5.36/gal (U.S. average, Sep 2026). Powertrains over the years: gas, hybrid and diesel. EPA changed the ratings in 2007, 2008, 2009, 2010 and 2011. The best combined rating in the generation, 22 MPG, was reached in 2010 and 2011.
EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.
2006-2011 Mercedes-Benz ML-Class by model year
| Model year | Powertrains | Combined | $/yr | EPA ratings |
|---|---|---|---|---|
| 2011 | Gas, Hybrid | 12–22 MPG | $3,680–$6,510 | Ratings changed |
| 2010 | Gas, Hybrid | 12–22 MPG | $3,650–$6,510 | Ratings changed |
| 2009 | Gas | 12–18 MPG | $4,460–$6,700 | Ratings changed |
| 2008 | Gas, Diesel | 12–21 MPG | $4,490–$6,700 | Ratings changed |
| 2007 | Gas, Diesel | 12–21 MPG | $4,490–$6,700 | Ratings changed |
| 2006 | Gas | 14–16 MPG | $5,020–$5,740 | First year |
What the 2011 ML350 3.5L 6-cyl RWD costs to drive
Per month
$383
$4,600 a year ÷ 12
Per 25 miles
$7.67
Per 100 miles
$30.67
Five years
$23,000
5 × the yearly cost, prices held at today's level
vs the standard SUV median
$1,120more a year
Class median $3,480 a year, MY2011
Based on 15,000 miles a year and premium gasoline $5.36/gal (U.S. average, Sep 2026).
2011 Mercedes-Benz ML-Class MPG
Versus 2010: The most efficient configuration stays at 22 MPG. Its annual cost goes from $3,650 to $3,680, $30 more.
Gas configurations (4)
| Trim | Engine | Drive | City | Hwy | Comb. | $/yr |
|---|---|---|---|---|---|---|
| ML350 (Most efficient) | 3.5L 6-cyl | RWD | 16 | 21 | 17 | $4,600 |
| ML350 4matic | 3.5L 6-cyl | RWD | 15 | 20 | 17 | $4,780 |
| ML550 4matic | 5.5L 8-cyl | 4WD | 13 | 18 | 15 | $5,290 |
| ML63 AMG | 6.3L 8-cyl | 4WD | 11 | 15 | 12 | $6,510 |
4 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).
Hybrid configurations (1)
| Trim | Engine | Drive | City | Hwy | Comb. | $/yr |
|---|---|---|---|---|---|---|
| ML450 Hybrid 4matic (Most efficient) | 3.5L 6-cyl | 4WD | 20 | 24 | 22 | $3,680 |
1 configuration requires or recommends higher-octane gasoline and is costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).
2010 Mercedes-Benz ML-Class MPG
12–22 MPG · $3,650–$6,510/yr
Versus 2009: The most efficient configuration moves from 18 to 22 MPG, up 4. Its annual cost goes from $4,460 to $3,650, $810 less.
Gas configurations (4)
| Trim | Engine | Drive | City | Hwy | Comb. | $/yr |
|---|---|---|---|---|---|---|
| ML350 (Most efficient) | 3.5L 6-cyl | RWD | 16 | 21 | 18 | $4,460 |
| ML350 4matic | 3.5L 6-cyl | 4WD | 15 | 20 | 17 | $4,730 |
| ML550 4matic | 5.5L 8-cyl | 4WD | 13 | 18 | 15 | $5,360 |
| ML63 AMG | 6.3L 8-cyl | 4WD | 11 | 15 | 12 | $6,510 |
4 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).
Hybrid configurations (1)
| Trim | Engine | Drive | City | Hwy | Comb. | $/yr |
|---|---|---|---|---|---|---|
| ML450 Hybrid 4matic (Most efficient) | 3.5L 6-cyl | 4WD | 21 | 24 | 22 | $3,650 |
1 configuration requires or recommends higher-octane gasoline and is costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).
2009 Mercedes-Benz ML-Class MPG
12–18 MPG · $4,460–$6,700/yr
Versus 2008: The most efficient configuration moves from 21 to 18 MPG, down 3. Its annual cost goes from $4,490 to $4,460, $30 less.
Gas configurations (4)
| Trim | Engine | Drive | City | Hwy | Comb. | $/yr |
|---|---|---|---|---|---|---|
| ML350 (Most efficient) | 3.5L 6-cyl | RWD | 16 | 21 | 18 | $4,460 |
| ML350 4matic | 3.5L 6-cyl | 4WD | 15 | 20 | 17 | $4,730 |
| ML550 4matic | 5.5L 8-cyl | 4WD | 13 | 18 | 15 | $5,360 |
| ML63 AMG | 6.2L 8-cyl | 4WD | 11 | 15 | 12 | $6,700 |
4 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).
2008 Mercedes-Benz ML-Class MPG
12–21 MPG · $4,490–$6,700/yr
Versus 2007: The most efficient configuration stays at 21 MPG. Its annual cost stays at $4,490.
Gas configurations (3)
| Trim | Engine | Drive | City | Hwy | Comb. | $/yr |
|---|---|---|---|---|---|---|
| ML350 4matic (Most efficient) | 3.5L 6-cyl | 4WD | 15 | 20 | 17 | $4,730 |
| ML550 4matic | 5.5L 8-cyl | 4WD | 13 | 18 | 15 | $5,360 |
| ML63 AMG | 6.2L 8-cyl | 4WD | 11 | 14 | 12 | $6,700 |
3 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).
Diesel configurations (1)
| Trim | Engine | Drive | City | Hwy | Comb. | $/yr |
|---|---|---|---|---|---|---|
| ML320 CDI 4matic (Most efficient) | 3.0L 6-cyl turbo | 4WD | 18 | 24 | 21 | $4,490 |
Diesel is priced at diesel $6.29/gal (U.S. average, Sep 2026).
2007 Mercedes-Benz ML-Class MPG
12–21 MPG · $4,490–$6,700/yr
EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.
Versus 2006: The most efficient configuration moves from 16 to 21 MPG, up 5. Its annual cost goes from $5,020 to $4,490, $530 less.
Gas configurations (3)
| Trim | Engine | Drive | City | Hwy | Comb. | $/yr |
|---|---|---|---|---|---|---|
| ML350 4matic (Most efficient) | 3.5L 6-cyl | 4WD | 15 | 20 | 17 | $4,730 |
| ML500 4matic | 5.0L 8-cyl | 4WD | 13 | 17 | 14 | $5,740 |
| ML63 AMG | 6.2L 8-cyl | 4WD | 11 | 14 | 12 | $6,700 |
3 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).
Diesel configurations (1)
| Trim | Engine | Drive | City | Hwy | Comb. | $/yr |
|---|---|---|---|---|---|---|
| ML320 CDI 4matic (Most efficient) | 3.0L 6-cyl turbo | 4WD | 19 | 24 | 21 | $4,490 |
Diesel is priced at diesel $6.29/gal (U.S. average, Sep 2026).
2006 Mercedes-Benz ML-Class MPG
14–16 MPG · $5,020–$5,740/yr
EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.
Gas configurations (2)
| Trim | Engine | Drive | City | Hwy | Comb. | $/yr |
|---|---|---|---|---|---|---|
| ML350 (Most efficient) | 3.5L 6-cyl | 4WD | 14 | 19 | 16 | $5,020 |
| ML500 | 5.0L 8-cyl | 4WD | 13 | 17 | 14 | $5,740 |
2 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).
Fuel cost by state
Yearly cost of the ML350 3.5L 6-cyl RWD: $5,480 in California and $3,990 in Texas, a $1,490 difference.
- California $5,480
- Washington $5,160
- New York $4,540
- Florida $4,200
- Texas $3,990
Similar cars
Closest combined MPG among MY2011 standard SUV models.
Generations
- 2000-2005 (W163)
- 2006-2011 (W164)
- 2012-2015 (W166)
Frequently asked questions
What gas mileage does the 2006-2011 Mercedes-Benz ML-Class get?
EPA rates the 2006-2011 Mercedes-Benz ML-Class at 12–22 MPG combined across 24 configurations and 6 model years. The most efficient version, the 2011 ML450 Hybrid 4matic 3.5L 6-cyl 4WD, is rated 22 MPG (20 city, 24 highway). By powertrain: Gas: 12–18 MPG; Hybrid: 22 MPG; Diesel: 21 MPG.
Which years had the best MPG in the 2006-2011 Mercedes-Benz ML-Class?
The ML450 Hybrid 4matic 3.5L 6-cyl 4WD reached the generation's best combined rating, 22 MPG, in 2010 and 2011. The lowest top rating, 16 MPG, was in 2006.
Did EPA ratings change during the 2006-2011 Mercedes-Benz ML-Class?
Yes. Ratings changed in 2007, 2008, 2009, 2010 and 2011.
How does the 2006-2011 Mercedes-Benz ML-Class compare with the previous generation?
The previous generation (2000-2005 Mercedes-Benz ML-Class) is rated 14–17 MPG combined and costs $4,730–$5,740 a year to fuel; the 2006-2011 model is rated 12–22 MPG and costs $3,650–$6,700 a year.
How much does it cost to fuel a 2011 Mercedes-Benz ML-Class per year?
Driving 15,000 miles a year at premium gasoline $5.36/gal (U.S. average, Sep 2026), the ML350 3.5L 6-cyl RWD costs about $4,600 a year. Across all 5 configurations the cost runs $3,680–$6,510 a year. That is a $2,830 difference between the cheapest and the costliest configuration.
How much does it cost to drive a 2011 Mercedes-Benz ML-Class 100 miles?
About $30.67 per 100 miles for the ML350 3.5L 6-cyl RWD at premium gasoline $5.36/gal (U.S. average, Sep 2026), and between $24.53 and $43.40 across all configurations. That is the annual cost over 15,000 miles divided by 150.
How does the 2011 Mercedes-Benz ML-Class compare with other standard SUV configurations?
The ML350 3.5L 6-cyl RWD costs about $4,600 a year to fuel, $1,120 more than the class median of $3,480, and less than 1 of 10 standard SUV configurations. The comparison covers all 307 rated standard SUV configurations for MY2011, not weighted by sales.
Is the 2011 Mercedes-Benz ML-Class hybrid cheaper to fuel than the gas version?
Yes. The best hybrid (ML450 Hybrid 4matic 3.5L 6-cyl 4WD) is rated 22 MPG against 17 MPG for the best gas version (ML350 3.5L 6-cyl RWD), 5 MPG more. At premium gasoline $5.36/gal (U.S. average, Sep 2026) that is $3,680 versus $4,600 a year, a saving of $920.
Is the 2011 Mercedes-Benz ML-Class different from the 2010 model?
The most efficient configuration stays at 22 MPG. Its annual cost goes from $3,650 to $3,680, $30 more. EPA lists 5 configurations for 2011 against 5 configurations for 2010. See the 2010 Mercedes-Benz ML-Class for that year.