Gallonly
2023 Mercedes-Benz CLS-Class
Shown: 2023 Mercedes-Benz CLS-Class. Photo: Calreyn88, CC BY-SA 4.0, via Wikimedia Commons
  • Hybrid
  • Small cars
  • MY2006–2023

Mercedes-Benz CLS-Class MPG & Fuel Cost by Year

18 model years · 2006–2023

25 MPG
Combined
22 MPG
City
30 MPG
Highway
Annual cost · MY2023 CLS450 4matic 3.0L 6-cyl turbo AWD
$3,240

15,000 mi/yr · premium gasoline $5.36/gal (U.S. average, Sep 2026)

All Mercedes-Benz models

Mercedes-Benz CLS-Class fuel economy at a glance

EPA has rated the Mercedes-Benz CLS-Class for 18 model years, 2006 to 2023. Across those years its combined rating runs 14–26 MPG. The latest model year, 2023, has 1 configuration rated 25 MPG combined and costing $3,240 a year to fuel at premium gasoline $5.36/gal (U.S. average, Sep 2026). The most efficient configuration on record since 2006 is the 2021 CLS450 3.0L 6-cyl turbo RWD, at 26 MPG.

Mercedes-Benz CLS-Class MPG by year

14161820222426 200620102012201520192023 Gas Hybrid 14161820222426 20062010201520192023 Gas Hybrid
Combined MPG: the line is the most efficient configuration, the shaded band reaches down to the least efficient. Dotted lines mark new generations.
Mercedes-Benz CLS-Class: combined fuel economy and annual fuel cost for each model year, grouped by generation
Year Gas (MPG)Hybrid (MPG) $/yr
2023 Generation page
2023 —25 $3,240
2022 Generation page
2022 —25 $3,240
2019-2021 Generation page
2021 —23–26 $3,140–$3,510
2020 —23–26 $3,030–$3,430
2019 —23–26 $3,030–$3,430
2015-2018 Generation page
2018 18–21— $3,830–$4,480
2017 18–21— $3,830–$4,480
2016 18–24— $3,400–$4,490
2015 18–24— $3,420–$4,480
2012-2014 Generation page
2014 18–20— $3,990–$4,480
2013 19–20— $4,110–$4,240
2012 19–20— $4,110–$4,230
2010-2011 Generation page
2011 14–16— $4,870–$5,660
2010 14–16— $5,020–$5,740
2007-2009 Generation page
2009 14–16— $5,020–$5,740
2008 14–16— $5,020–$5,740
2007 14–16— $5,020–$5,740
2006 Generation page
2006 15–16— $5,020–$5,360

Costs use the current EIA price set and 15,000 miles a year for every year, so years are comparable. Green marks the best year for each powertrain.

Mercedes-Benz CLS-Class generations

8 generations between 2006 and 2023. Open one for the table of every model year and configuration.

2023 powertrain options

Hybrid · 3.0L
Combined
25 MPG
Per year
$3,240
See hybrid configurations
EPA ratings: fueleconomy.gov file of Sep 29, 2026 · premium gasoline $5.36/gal (U.S. average, Sep 2026) · 15,000 mi/yr, 55% city / 45% highway · How we calculate

Frequently asked questions

What is the Mercedes-Benz CLS-Class's gas mileage by year?

EPA combined ratings for the Mercedes-Benz CLS-Class run 14–26 MPG across model years 2006 to 2023. The latest year, 2023, is rated 25 MPG.

Which Mercedes-Benz CLS-Class model year has the best gas mileage?

The 2021 Mercedes-Benz CLS-Class CLS450 3.0L 6-cyl turbo RWD has the highest combined rating since 2006, at 26 MPG.

How much does a Mercedes-Benz CLS-Class cost to fuel per year?

For MY2023, EPA-rated configurations cost $3,240 a year to fuel, driving 15,000 miles at premium gasoline $5.36/gal (U.S. average, Sep 2026). The most efficient one costs $3,240.

Has the Mercedes-Benz CLS-Class's fuel economy improved over time?

Yes. The most efficient configuration moved from 16 MPG in 2006 to 25 MPG in 2023, 9 MPG more.

Is there a hybrid, plug-in or electric Mercedes-Benz CLS-Class?

Yes. Hybrid versions are rated from 2019 to 2023 (23–26 MPG).

Which Mercedes-Benz CLS-Class model years have the same ratings?

EPA lists identical ratings as the previous year for 2009, 2018, 2020. The generation pages mark those years "same EPA ratings" and point to the year that holds the full table.

How many generations of the Mercedes-Benz CLS-Class are there?

EPA data covers 8 generations of the Mercedes-Benz CLS-Class: 2023, 2022, 2019-2021, 2015-2018, 2012-2014, 2010-2011, 2007-2009, 2006. Each has its own page with a table for every model year.