- Hybrid
- Small cars
- MY2006–2023
Mercedes-Benz CLS-Class MPG & Fuel Cost by Year
18 model years · 2006–2023
15,000 mi/yr · premium gasoline $5.36/gal (U.S. average, Sep 2026)
Mercedes-Benz CLS-Class fuel economy at a glance
EPA has rated the Mercedes-Benz CLS-Class for 18 model years, 2006 to 2023. Across those years its combined rating runs 14–26 MPG. The latest model year, 2023, has 1 configuration rated 25 MPG combined and costing $3,240 a year to fuel at premium gasoline $5.36/gal (U.S. average, Sep 2026). The most efficient configuration on record since 2006 is the 2021 CLS450 3.0L 6-cyl turbo RWD, at 26 MPG.
Mercedes-Benz CLS-Class MPG by year
| Year | Gas (MPG) | Hybrid (MPG) | $/yr |
|---|---|---|---|
| 2023 Generation page | |||
| 2023 | — | 25 | $3,240 |
| 2022 Generation page | |||
| 2022 | — | 25 | $3,240 |
| 2019-2021 Generation page | |||
| 2021 | — | 23–26 | $3,140–$3,510 |
| 2020 | — | 23–26 | $3,030–$3,430 |
| 2019 | — | 23–26 | $3,030–$3,430 |
| 2015-2018 Generation page | |||
| 2018 | 18–21 | — | $3,830–$4,480 |
| 2017 | 18–21 | — | $3,830–$4,480 |
| 2016 | 18–24 | — | $3,400–$4,490 |
| 2015 | 18–24 | — | $3,420–$4,480 |
| 2012-2014 Generation page | |||
| 2014 | 18–20 | — | $3,990–$4,480 |
| 2013 | 19–20 | — | $4,110–$4,240 |
| 2012 | 19–20 | — | $4,110–$4,230 |
| 2010-2011 Generation page | |||
| 2011 | 14–16 | — | $4,870–$5,660 |
| 2010 | 14–16 | — | $5,020–$5,740 |
| 2007-2009 Generation page | |||
| 2009 | 14–16 | — | $5,020–$5,740 |
| 2008 | 14–16 | — | $5,020–$5,740 |
| 2007 | 14–16 | — | $5,020–$5,740 |
| 2006 Generation page | |||
| 2006 | 15–16 | — | $5,020–$5,360 |
Costs use the current EIA price set and 15,000 miles a year for every year, so years are comparable. Green marks the best year for each powertrain.
Mercedes-Benz CLS-Class generations
8 generations between 2006 and 2023. Open one for the table of every model year and configuration.
2023 Mercedes-Benz CLS-Class
25 MPG · $3,240/yr
2022 Mercedes-Benz CLS-Class
25 MPG · $3,240/yr
2019-2021 Mercedes-Benz CLS-Class
23–26 MPG · $3,030–$3,510/yr
2015-2018 Mercedes-Benz CLS-Class
18–24 MPG · $3,400–$4,490/yr
2012-2014 Mercedes-Benz CLS-Class
18–20 MPG · $3,990–$4,480/yr
2010-2011 Mercedes-Benz CLS-Class
14–16 MPG · $4,870–$5,740/yr
2007-2009 Mercedes-Benz CLS-Class
14–16 MPG · $5,020–$5,740/yr
2006 Mercedes-Benz CLS-Class
15–16 MPG · $5,020–$5,360/yr
2023 powertrain options
Frequently asked questions
What is the Mercedes-Benz CLS-Class's gas mileage by year?
EPA combined ratings for the Mercedes-Benz CLS-Class run 14–26 MPG across model years 2006 to 2023. The latest year, 2023, is rated 25 MPG.
Which Mercedes-Benz CLS-Class model year has the best gas mileage?
The 2021 Mercedes-Benz CLS-Class CLS450 3.0L 6-cyl turbo RWD has the highest combined rating since 2006, at 26 MPG.
How much does a Mercedes-Benz CLS-Class cost to fuel per year?
For MY2023, EPA-rated configurations cost $3,240 a year to fuel, driving 15,000 miles at premium gasoline $5.36/gal (U.S. average, Sep 2026). The most efficient one costs $3,240.
Has the Mercedes-Benz CLS-Class's fuel economy improved over time?
Yes. The most efficient configuration moved from 16 MPG in 2006 to 25 MPG in 2023, 9 MPG more.
Is there a hybrid, plug-in or electric Mercedes-Benz CLS-Class?
Yes. Hybrid versions are rated from 2019 to 2023 (23–26 MPG).
Which Mercedes-Benz CLS-Class model years have the same ratings?
EPA lists identical ratings as the previous year for 2009, 2018, 2020. The generation pages mark those years "same EPA ratings" and point to the year that holds the full table.