- Newest year: 2010
- Gas
- Large cars
2006-2010 Infiniti M45 MPG & Fuel Cost
5 model years · 16–18 MPG combined
15,000 mi/yr · premium gasoline $5.36/gal (U.S. average, Sep 2026)
Cheaper to fuel than 3 of 10 large car configurations, MY2010. Ranked against all rated configurations, not sales-weighted.
2006-2010 Infiniti M45 at a glance
The 2006-2010 Infiniti M45 covers 5 model years in the EPA database (8 configurations in all), rated 16–18 MPG combined. The newest model year, 2010, costs about $4,460 a year to fuel for its most efficient version, the M45 4.5L 8-cyl RWD (18 MPG), at premium gasoline $5.36/gal (U.S. average, Sep 2026). EPA changed the ratings in 2008 and 2010; 2007 and 2009 repeat the values of the year before.
EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.
2006-2010 Infiniti M45 by model year
| Model year | Powertrains | Combined | $/yr | EPA ratings |
|---|---|---|---|---|
| 2010 | Gas | 16–18 MPG | $4,460–$5,020 | Ratings changed |
| 2009 | Gas | 16–18 MPG | $4,460–$5,020 | Same EPA ratings as 2008 |
| 2008 | Gas | 16–18 MPG | $4,460–$5,020 | Ratings changed |
| 2007 | Gas | 18 MPG | $4,460 | Same EPA ratings as 2006 |
| 2006 | Gas | 18 MPG | $4,460 | First year |
What the 2010 M45 4.5L 8-cyl RWD costs to drive
Per month
$372
$4,460 a year ÷ 12
Per 25 miles
$7.43
Per 100 miles
$29.73
Five years
$22,300
5 × the yearly cost, prices held at today's level
vs the large car median
$830more a year
Class median $3,630 a year, MY2010
Based on 15,000 miles a year and premium gasoline $5.36/gal (U.S. average, Sep 2026).
2010 Infiniti M45 MPG
Versus 2009: The most efficient configuration stays at 18 MPG. Its annual cost stays at $4,460.
Gas configurations (2)
| Trim | Engine | Drive | City | Hwy | Comb. | $/yr |
|---|---|---|---|---|---|---|
| M45 (Most efficient) | 4.5L 8-cyl | RWD | 16 | 21 | 18 | $4,460 |
| M45x | 4.5L 8-cyl | AWD | 14 | 20 | 16 | $5,020 |
2 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).
2009 Infiniti M45 MPG
Same EPA ratings as 2008
EPA lists the same ratings for the 2009 Infiniti M45 as for the 2008 model, so the configurations and costs are the ones in the 2008 section above.See 2008
2008 Infiniti M45 MPG
16–18 MPG · $4,460–$5,020/yr
Versus 2007: The most efficient configuration stays at 18 MPG. Its annual cost stays at $4,460.
Gas configurations (2)
| Trim | Engine | Drive | City | Hwy | Comb. | $/yr |
|---|---|---|---|---|---|---|
| M45 (Most efficient) | 4.5L 8-cyl | RWD | 16 | 21 | 18 | $4,460 |
| M45x | 4.5L 8-cyl | 4WD | 14 | 20 | 16 | $5,020 |
2 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).
2007 Infiniti M45 MPG
Same EPA ratings as 2006
EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.
EPA lists the same ratings for the 2007 Infiniti M45 as for the 2006 model, so the configurations and costs are the ones in the 2006 section above.See 2006
2006 Infiniti M45 MPG
18 MPG · $4,460/yr
EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.
Gas configurations (1)
| Trim | Engine | Drive | City | Hwy | Comb. | $/yr |
|---|---|---|---|---|---|---|
| M45 (Most efficient) | 4.5L 8-cyl | RWD | 16 | 21 | 18 | $4,460 |
1 configuration requires or recommends higher-octane gasoline and is costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).
Fuel cost by state
Yearly cost of the M45 4.5L 8-cyl RWD: $5,320 in California and $3,870 in Texas, a $1,450 difference.
- California $5,320
- Washington $5,010
- New York $4,410
- Florida $4,080
- Texas $3,870
Similar cars
Closest combined MPG among MY2010 large car models.
Generations
- 2003-2004 (2nd gen)
- 2006-2010 (3rd gen)
Frequently asked questions
What gas mileage does the 2006-2010 Infiniti M45 get?
EPA rates the 2006-2010 Infiniti M45 at 16–18 MPG combined across 8 configurations and 5 model years. The most efficient version, the 2010 M45 4.5L 8-cyl RWD, is rated 18 MPG (16 city, 21 highway).
Which years had the best MPG in the 2006-2010 Infiniti M45?
Every model year of the 2006-2010 Infiniti M45 tops out at 18 MPG combined, so no year is better than another.
Did EPA ratings change during the 2006-2010 Infiniti M45?
Yes. Ratings changed in 2008 and 2010. In 2007 and 2009 the values repeat the year before.
How does the 2006-2010 Infiniti M45 compare with the previous generation?
The previous generation (2003-2004 Infiniti M45) is rated 18 MPG combined and costs $4,460 a year to fuel; the 2006-2010 model is rated 16–18 MPG and costs $4,460–$5,020 a year.
How much does it cost to fuel a 2010 Infiniti M45 per year?
Driving 15,000 miles a year at premium gasoline $5.36/gal (U.S. average, Sep 2026), the M45 4.5L 8-cyl RWD costs about $4,460 a year. Across all 2 configurations the cost runs $4,460–$5,020 a year. That is a $560 difference between the cheapest and the costliest configuration.
How much does it cost to drive a 2010 Infiniti M45 100 miles?
About $29.73 per 100 miles for the M45 4.5L 8-cyl RWD at premium gasoline $5.36/gal (U.S. average, Sep 2026), and between $29.73 and $33.47 across all configurations. That is the annual cost over 15,000 miles divided by 150.
Is the 2010 Infiniti M45 more efficient in the city or on the highway?
The M45 4.5L 8-cyl RWD is rated 16 city and 21 highway MPG, so it is more efficient on the highway, by 5 MPG.
How does the 2010 Infiniti M45 compare with other large car configurations?
The M45 4.5L 8-cyl RWD costs about $4,460 a year to fuel, $830 more than the class median of $3,630, and less than 3 of 10 large car configurations. The comparison covers all 67 rated large car configurations for MY2010, not weighted by sales.
Is the 2010 Infiniti M45 different from the 2009 model?
The most efficient configuration stays at 18 MPG. Its annual cost stays at $4,460. EPA lists 2 configurations for 2010 against 2 configurations for 2009. See the 2009 Infiniti M45 for that year.