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2020 Mercedes-Benz GLS 450 (X167)
Shown: 2020 Mercedes-Benz GLS 450 (X167). Photo: Kevauto, CC BY-SA 4.0, via Wikimedia Commons
  • Newest year: 2027
  • Hybrid
  • Standard SUVs
  • Partial model year

2020-2027 Mercedes-Benz GLS-Class MPG & Fuel Cost

8 model years · 15–21 MPG combined

21 MPG
Combined
19 MPG
City
24 MPG
Highway
Annual fuel cost · GLS450 4matic 3.0L 6-cyl turbo supercharged AWD
$3,880

15,000 mi/yr · premium gasoline $5.36/gal (U.S. average, Sep 2026)

Cheaper to fuel than 3 of 10 standard SUV configurations, MY2027. Ranked against all rated configurations, not sales-weighted.

2020-2027 Mercedes-Benz GLS-Class at a glance

The 2020-2027 Mercedes-Benz GLS-Class covers 8 model years in the EPA database (27 configurations in all), rated 15–21 MPG combined. The newest model year, 2027, costs about $3,880 a year to fuel for its most efficient version, the GLS450 4matic 3.0L 6-cyl turbo supercharged AWD (21 MPG), at premium gasoline $5.36/gal (U.S. average, Sep 2026). EPA changed the ratings in 2021, 2022, 2023, 2024, 2025, 2026 and 2027. The best combined rating in the generation, 21 MPG, was reached in 2020, 2021, 2024, 2025, 2026 and 2027.

Model year 2027 is still being filled in by EPA (1 configuration listed so far), so rows may be added.

2020-2027 Mercedes-Benz GLS-Class by model year

2020-2027 Mercedes-Benz GLS-Class: EPA combined rating and yearly fuel cost for each model year
Model yearPowertrainsCombined$/yrEPA ratings
2027 (partial) Hybrid 21 MPG $3,880 Ratings changed
2026 Hybrid 15–21 MPG $3,860–$5,310 Ratings changed
2025 Hybrid 15–21 MPG $3,860–$5,350 Ratings changed
2024 Hybrid 16–21 MPG $3,860–$5,180 Ratings changed
2023 Hybrid 16–20 MPG $3,950–$5,070 Ratings changed
2022 Hybrid 15–20 MPG $3,940–$5,190 Ratings changed
2021 Hybrid 16–21 MPG $3,750–$5,050 Ratings changed
2020 Hybrid 18–21 MPG $3,880–$4,430 First year

What the 2027 GLS450 4matic 3.0L 6-cyl turbo supercharged AWD costs to drive

Per month

$323

$3,880 a year ÷ 12

Per 25 miles

$6.47

Per 100 miles

$25.87

Five years

$19,400

5 × the yearly cost, prices held at today's level

vs the standard SUV median

$720more a year

Class median $3,160 a year, MY2027

Based on 15,000 miles a year and premium gasoline $5.36/gal (U.S. average, Sep 2026).

2027 Mercedes-Benz GLS-Class MPG

Model year 2027 is still being filled in by EPA (1 configuration listed so far), so rows may be added.

Versus 2026: The most efficient configuration stays at 21 MPG. Its annual cost goes from $3,860 to $3,880, $20 more.

Hybrid · 3.0L
Combined
21 MPG
Per year
$3,880

Hybrid configurations (1)

2027 Mercedes-Benz GLS-Class hybrid configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
GLS450 4matic (Most efficient) 3.0L 6-cyl turbo supercharged AWD 19 24 21 $3,880

1 configuration requires or recommends higher-octane gasoline and is costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2026 Mercedes-Benz GLS-Class MPG

15–21 MPG · $3,860–$5,310/yr

Versus 2025: The most efficient configuration stays at 21 MPG. Its annual cost stays at $3,860.

Hybrid · 3.0L, 4.0L
Combined
15–21 MPG
Per year
$3,860–$5,310

Hybrid configurations (4)

2026 Mercedes-Benz GLS-Class hybrid configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
GLS450 4matic (Most efficient) 3.0L 6-cyl turbo supercharged AWD 19 24 21 $3,860
AMG GLS63 4matic Plus 4.0L 8-cyl turbo AWD 15 20 17 $4,850
GLS580 4matic 4.0L 8-cyl turbo AWD 14 20 16 $4,880
GLS600 4matic Maybach 4.0L 8-cyl turbo AWD 13 18 15 $5,310

4 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2025 Mercedes-Benz GLS-Class MPG

15–21 MPG · $3,860–$5,350/yr

Versus 2024: The most efficient configuration stays at 21 MPG. Its annual cost stays at $3,860.

Hybrid · 3.0L, 4.0L
Combined
15–21 MPG
Per year
$3,860–$5,350

Hybrid configurations (4)

2025 Mercedes-Benz GLS-Class hybrid configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
GLS450 4matic (Most efficient) 3.0L 6-cyl turbo supercharged AWD 19 24 21 $3,860
GLS580 4matic 4.0L 8-cyl turbo AWD 14 19 16 $4,990
AMG GLS63 4matic Plus 4.0L 8-cyl turbo AWD 14 18 15 $5,240
GLS600 4matic Maybach 4.0L 8-cyl turbo AWD 13 18 15 $5,350

4 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2024 Mercedes-Benz GLS-Class MPG

16–21 MPG · $3,860–$5,180/yr

Versus 2023: The most efficient configuration moves from 20 to 21 MPG, up 1. Its annual cost goes from $3,950 to $3,860, $90 less.

Hybrid · 3.0L, 4.0L
Combined
16–21 MPG
Per year
$3,860–$5,180

Hybrid configurations (4)

2024 Mercedes-Benz GLS-Class hybrid configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
GLS450 4matic (Most efficient) 3.0L 6-cyl turbo AWD 19 24 21 $3,860
GLS580 4matic 4.0L 8-cyl turbo AWD 14 20 16 $5,000
AMG GLS63 4matic Plus 4.0L 8-cyl turbo AWD 14 18 16 $5,090
GLS600 4matic Maybach 4.0L 8-cyl turbo AWD 14 19 16 $5,180

4 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2023 Mercedes-Benz GLS-Class MPG

16–20 MPG · $3,950–$5,070/yr

Versus 2022: The most efficient configuration stays at 20 MPG. Its annual cost goes from $3,940 to $3,950, $10 more.

Hybrid · 3.0L, 4.0L
Combined
16–20 MPG
Per year
$3,950–$5,070

Hybrid configurations (4)

2023 Mercedes-Benz GLS-Class hybrid configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
GLS450 4matic (Most efficient) 3.0L 6-cyl turbo AWD 18 23 20 $3,950
GLS580 4matic 4.0L 8-cyl turbo AWD 16 21 18 $4,520
GLS600 4matic Maybach 4.0L 8-cyl turbo AWD 15 20 17 $4,790
AMG GLS63 4matic Plus 4.0L 8-cyl turbo AWD 14 19 16 $5,070

4 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2022 Mercedes-Benz GLS-Class MPG

15–20 MPG · $3,940–$5,190/yr

Versus 2021: The most efficient configuration moves from 21 to 20 MPG, down 1. Its annual cost goes from $3,750 to $3,940, $190 more.

Hybrid · 3.0L, 4.0L
Combined
15–20 MPG
Per year
$3,940–$5,190

Hybrid configurations (4)

2022 Mercedes-Benz GLS-Class hybrid configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
GLS450 4matic (Most efficient) 3.0L 6-cyl turbo 4WD 18 24 20 $3,940
GLS580 4matic 4.0L 8-cyl turbo AWD 16 21 18 $4,540
GLS600 4matic Maybach 4.0L 8-cyl turbo AWD 14 20 17 $4,870
AMG GLS63 4matic Plus 4.0L 8-cyl turbo AWD 14 18 15 $5,190

4 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2021 Mercedes-Benz GLS-Class MPG

16–21 MPG · $3,750–$5,050/yr

Versus 2020: The most efficient configuration stays at 21 MPG. Its annual cost goes from $3,880 to $3,750, $130 less.

Hybrid · 3.0L, 4.0L
Combined
16–21 MPG
Per year
$3,750–$5,050

Hybrid configurations (4)

2021 Mercedes-Benz GLS-Class hybrid configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
GLS450 4matic (Most efficient) 3.0L 6-cyl turbo 4WD 20 24 21 $3,750
GLS580 4matic 4.0L 8-cyl turbo 4WD 16 21 18 $4,450
GLS600 4matic Maybach 4.0L 8-cyl turbo 4WD 15 19 16 $4,870
AMG GLS63 4matic Plus 4.0L 8-cyl turbo 4WD 14 18 16 $5,050

4 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2020 Mercedes-Benz GLS-Class MPG

18–21 MPG · $3,880–$4,430/yr
Hybrid · 3.0L, 4.0L
Combined
18–21 MPG
Per year
$3,880–$4,430

Hybrid configurations (2)

2020 Mercedes-Benz GLS-Class hybrid configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
GLS450 4matic (Most efficient) 3.0L 6-cyl turbo 4WD 19 23 21 $3,880
GLS580 4matic 4.0L 8-cyl turbo 4WD 16 21 18 $4,430

2 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

Fuel cost by state

Yearly cost of the GLS450 4matic 3.0L 6-cyl turbo supercharged AWD: $4,630 in California and $3,370 in Texas, a $1,260 difference.

Gasoline prices: California: California state average; Washington: Washington state average; New York: New York state average; Florida: Florida state average; Texas: Texas state average (Sep 2026).
Fuel cost in every state

Similar cars

Closest combined MPG among MY2027 standard SUV models.

EPA ratings: fueleconomy.gov file of Sep 29, 2026 · Prices: EIA regular gasoline, U.S. average, Sep 2026 ($4.36/gal) · 15,000 mi/yr, 55% city / 45% highway · How we calculate

Generations

Frequently asked questions

What gas mileage does the 2020-2027 Mercedes-Benz GLS-Class get?

EPA rates the 2020-2027 Mercedes-Benz GLS-Class at 15–21 MPG combined across 27 configurations and 8 model years. The most efficient version, the 2027 GLS450 4matic 3.0L 6-cyl turbo supercharged AWD, is rated 21 MPG (19 city, 24 highway).

Which years had the best MPG in the 2020-2027 Mercedes-Benz GLS-Class?

The GLS450 4matic 3.0L 6-cyl turbo supercharged AWD reached the generation's best combined rating, 21 MPG, in 2020, 2021, 2024, 2025, 2026 and 2027. The lowest top rating, 20 MPG, was in 2022 and 2023.

Did EPA ratings change during the 2020-2027 Mercedes-Benz GLS-Class?

Yes. Ratings changed in 2021, 2022, 2023, 2024, 2025, 2026 and 2027.

How does the 2020-2027 Mercedes-Benz GLS-Class compare with the previous generation?

The previous generation (2017-2019 Mercedes-Benz GLS-Class) is rated 14–19 MPG combined and costs $4,320–$5,570 a year to fuel; the 2020-2027 model is rated 15–21 MPG and costs $3,750–$5,350 a year.

How much does it cost to fuel a 2027 Mercedes-Benz GLS-Class per year?

Driving 15,000 miles a year at premium gasoline $5.36/gal (U.S. average, Sep 2026), the GLS450 4matic 3.0L 6-cyl turbo supercharged AWD costs about $3,880 a year. Across all 1 configuration the cost runs $3,880 a year.

How much does it cost to drive a 2027 Mercedes-Benz GLS-Class 100 miles?

About $25.87 per 100 miles for the GLS450 4matic 3.0L 6-cyl turbo supercharged AWD at premium gasoline $5.36/gal (U.S. average, Sep 2026). That is the annual cost over 15,000 miles divided by 150.

Is the 2027 Mercedes-Benz GLS-Class more efficient in the city or on the highway?

The GLS450 4matic 3.0L 6-cyl turbo supercharged AWD is rated 19 city and 24 highway MPG, so it is more efficient on the highway, by 5 MPG.

How does the 2027 Mercedes-Benz GLS-Class compare with other standard SUV configurations?

The GLS450 4matic 3.0L 6-cyl turbo supercharged AWD costs about $3,880 a year to fuel, $720 more than the class median of $3,160, and less than 3 of 10 standard SUV configurations. The comparison covers all 184 rated standard SUV configurations for MY2027, not weighted by sales.

Is the 2027 Mercedes-Benz GLS-Class different from the 2026 model?

The most efficient configuration stays at 21 MPG. Its annual cost goes from $3,860 to $3,880, $20 more. EPA lists 1 configuration for 2027 against 4 configurations for 2026. See the 2026 Mercedes-Benz GLS-Class for that year.