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2017 Mercedes-Benz GLS 450 wagon (White)
Shown: 2017 Mercedes-Benz GLS 450 wagon (White). Photo: Mr.choppers, CC BY-SA 3.0, via Wikimedia Commons
  • Newest year: 2019
  • Gas
  • Standard SUVs

2017-2019 Mercedes-Benz GLS-Class MPG & Fuel Cost

3 model years · 14–19 MPG combined

18 MPG
Combined
16 MPG
City
22 MPG
Highway
Annual fuel cost · GLS450 4matic 3.0L 6-cyl turbo 4WD
$4,410

15,000 mi/yr · premium gasoline $5.36/gal (U.S. average, Sep 2026)

Cheaper to fuel than 3 of 10 standard SUV configurations, MY2019. Ranked against all rated configurations, not sales-weighted.

2017-2019 Mercedes-Benz GLS-Class at a glance

The 2017-2019 Mercedes-Benz GLS-Class covers 3 model years in the EPA database (9 configurations in all), rated 14–19 MPG combined. The newest model year, 2019, costs about $4,410 a year to fuel for its most efficient version, the GLS450 4matic 3.0L 6-cyl turbo 4WD (18 MPG), at premium gasoline $5.36/gal (U.S. average, Sep 2026). EPA changed the ratings in 2018 and 2019. The best combined rating in the generation, 19 MPG, was reached in 2017 and 2018.

2017-2019 Mercedes-Benz GLS-Class by model year

2017-2019 Mercedes-Benz GLS-Class: EPA combined rating and yearly fuel cost for each model year
Model yearPowertrainsCombined$/yrEPA ratings
2019 Gas 15–18 MPG $4,410–$5,430 Ratings changed
2018 Gas 15–19 MPG $4,320–$5,360 Ratings changed
2017 Gas 14–19 MPG $4,320–$5,570 First year

What the 2019 GLS450 4matic 3.0L 6-cyl turbo 4WD costs to drive

Per month

$368

$4,410 a year ÷ 12

Per 25 miles

$7.35

Per 100 miles

$29.40

Five years

$22,050

5 × the yearly cost, prices held at today's level

vs the standard SUV median

$640more a year

Class median $3,770 a year, MY2019

Based on 15,000 miles a year and premium gasoline $5.36/gal (U.S. average, Sep 2026).

2019 Mercedes-Benz GLS-Class MPG

Versus 2018: The most efficient configuration moves from 19 to 18 MPG, down 1. Its annual cost goes from $4,320 to $4,410, $90 more.

Gas · 3.0L, 4.7L, 5.5L
Combined
15–18 MPG
Per year
$4,410–$5,430

Gas configurations (3)

2019 Mercedes-Benz GLS-Class gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
GLS450 4matic (Most efficient) 3.0L 6-cyl turbo 4WD 16 22 18 $4,410
GLS550 4matic 4.7L 8-cyl turbo 4WD 14 19 16 $5,160
AMG GLS63 5.5L 8-cyl turbo 4WD 13 18 15 $5,430

3 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2018 Mercedes-Benz GLS-Class MPG

15–19 MPG · $4,320–$5,360/yr

Versus 2017: The most efficient configuration stays at 19 MPG. Its annual cost stays at $4,320.

Gas · 3.0L, 4.7L, 5.5L
Combined
15–19 MPG
Per year
$4,320–$5,360

Gas configurations (3)

2018 Mercedes-Benz GLS-Class gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
GLS450 4matic (Most efficient) 3.0L 6-cyl turbo 4WD 17 22 19 $4,320
GLS550 4matic 4.7L 8-cyl turbo 4WD 14 19 16 $5,040
AMG GLS63 5.5L 8-cyl turbo 4WD 13 18 15 $5,360

3 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2017 Mercedes-Benz GLS-Class MPG

14–19 MPG · $4,320–$5,570/yr
Gas · 3.0L, 4.7L, 5.5L
Combined
14–19 MPG
Per year
$4,320–$5,570

Gas configurations (3)

2017 Mercedes-Benz GLS-Class gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
GLS450 4matic (Most efficient) 3.0L 6-cyl turbo 4WD 17 22 19 $4,320
GLS550 4matic 4.7L 8-cyl turbo 4WD 14 18 16 $5,110
AMG GLS63 5.5L 8-cyl turbo 4WD 13 17 14 $5,570

3 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

Fuel cost by state

Yearly cost of the GLS450 4matic 3.0L 6-cyl turbo 4WD: $5,260 in California and $3,830 in Texas, a $1,430 difference.

Gasoline prices: California: California state average; Washington: Washington state average; New York: New York state average; Florida: Florida state average; Texas: Texas state average (Sep 2026).
Fuel cost in every state

Similar cars

Closest combined MPG among MY2019 standard SUV models.

EPA ratings: fueleconomy.gov file of Sep 29, 2026 · Prices: EIA regular gasoline, U.S. average, Sep 2026 ($4.36/gal) · 15,000 mi/yr, 55% city / 45% highway · How we calculate

Generations

Frequently asked questions

What gas mileage does the 2017-2019 Mercedes-Benz GLS-Class get?

EPA rates the 2017-2019 Mercedes-Benz GLS-Class at 14–19 MPG combined across 9 configurations and 3 model years. The most efficient version, the 2018 GLS450 4matic 3.0L 6-cyl turbo 4WD, is rated 19 MPG (17 city, 22 highway).

Which years had the best MPG in the 2017-2019 Mercedes-Benz GLS-Class?

The GLS450 4matic 3.0L 6-cyl turbo 4WD reached the generation's best combined rating, 19 MPG, in 2017 and 2018. The lowest top rating, 18 MPG, was in 2019.

Did EPA ratings change during the 2017-2019 Mercedes-Benz GLS-Class?

Yes. Ratings changed in 2018 and 2019.

How much does it cost to fuel a 2019 Mercedes-Benz GLS-Class per year?

Driving 15,000 miles a year at premium gasoline $5.36/gal (U.S. average, Sep 2026), the GLS450 4matic 3.0L 6-cyl turbo 4WD costs about $4,410 a year. Across all 3 configurations the cost runs $4,410–$5,430 a year. That is a $1,020 difference between the cheapest and the costliest configuration.

How much does it cost to drive a 2019 Mercedes-Benz GLS-Class 100 miles?

About $29.40 per 100 miles for the GLS450 4matic 3.0L 6-cyl turbo 4WD at premium gasoline $5.36/gal (U.S. average, Sep 2026), and between $29.40 and $36.20 across all configurations. That is the annual cost over 15,000 miles divided by 150.

Is the 2019 Mercedes-Benz GLS-Class more efficient in the city or on the highway?

The GLS450 4matic 3.0L 6-cyl turbo 4WD is rated 16 city and 22 highway MPG, so it is more efficient on the highway, by 6 MPG.

How does the 2019 Mercedes-Benz GLS-Class compare with other standard SUV configurations?

The GLS450 4matic 3.0L 6-cyl turbo 4WD costs about $4,410 a year to fuel, $640 more than the class median of $3,770, and less than 3 of 10 standard SUV configurations. The comparison covers all 151 rated standard SUV configurations for MY2019, not weighted by sales.

Is the 2019 Mercedes-Benz GLS-Class different from the 2018 model?

The most efficient configuration moves from 19 to 18 MPG, down 1. Its annual cost goes from $4,320 to $4,410, $90 more. EPA lists 3 configurations for 2019 against 3 configurations for 2018. See the 2018 Mercedes-Benz GLS-Class for that year.