2014-2026 Lexus IS MPG & Fuel Cost

EPA rates the 2014-2026 Lexus IS at 20–26 MPG combined across 58 configurations and 13 model years. The most efficient version, the 2018 300 2.0L 4-cyl turbo RWD, is rated 26 MPG (22 city, 32 highway).

The 300 2.0L 4-cyl turbo RWD reached the generation's best combined rating, 26 MPG, in 2016, 2017 and 2018. The lowest top rating, 22 MPG, was in 2026.

Yes. Ratings changed in 2015, 2016, 2017, 2018, 2019, 2020, 2021, 2022, 2023, 2024, 2025 and 2026.

The previous generation (2006-2013 Lexus IS) is rated 20–24 MPG combined and costs $3,300–$4,020 a year to fuel; the 2014-2026 model is rated 20–26 MPG and costs $3,120–$4,080 a year.

Driving 15,000 miles a year at premium gasoline $5.36/gal (U.S. average, Sep 2026), the 350 3.5L 6-cyl RWD costs about $3,660 a year. Across all 2 configurations the cost runs $3,660–$3,700 a year. That is a $40 difference between the cheapest and the costliest configuration.

About $24.40 per 100 miles for the 350 3.5L 6-cyl RWD at premium gasoline $5.36/gal (U.S. average, Sep 2026), and between $24.40 and $24.67 across all configurations. That is the annual cost over 15,000 miles divided by 150.

The 350 3.5L 6-cyl RWD is rated 19 city and 27 highway MPG, so it is more efficient on the highway, by 8 MPG.

The 350 3.5L 6-cyl RWD costs about $3,660 a year to fuel, $760 more than the class median of $2,900, and less than 3 of 10 small car configurations. The comparison covers all 195 rated small car configurations for MY2026, not weighted by sales.

The most efficient configuration moves from 25 to 22 MPG, down 3. Its annual cost goes from $3,240 to $3,660, $420 more. EPA lists 2 configurations for 2026 against 5 configurations for 2025. See the 2025 Lexus IS for that year.