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2020 Audi S5 Edition 1 Coupe facelift
Shown: 2020 Audi S5 Edition 1 Coupe facelift. Photo: Vauxford, CC BY-SA 4.0, via Wikimedia Commons
  • Newest year: 2021
  • Gas
  • Small cars

2019-2021 Audi S5 MPG & Fuel Cost

3 model years · 22–24 MPG combined

23 MPG
Combined
20 MPG
City
28 MPG
Highway
Annual fuel cost · S5 3.0L 6-cyl turbo AWD
$3,460

15,000 mi/yr · premium gasoline $5.36/gal (U.S. average, Sep 2026)

Cheaper to fuel than 4 of 10 small car configurations, MY2021. Ranked against all rated configurations, not sales-weighted.

2019-2021 Audi S5 at a glance

The 2019-2021 Audi S5 covers 3 model years in the EPA database (9 configurations in all), rated 22–24 MPG combined. The newest model year, 2021, costs about $3,460 a year to fuel for its most efficient version, the S5 3.0L 6-cyl turbo AWD (23 MPG), at premium gasoline $5.36/gal (U.S. average, Sep 2026). EPA changed the ratings in 2020 and 2021. The best combined rating in the generation, 24 MPG, was reached in 2019.

2019-2021 Audi S5 by model year

2019-2021 Audi S5: EPA combined rating and yearly fuel cost for each model year
Model yearPowertrainsCombined$/yrEPA ratings
2021 Gas 22–23 MPG $3,460–$3,570 Ratings changed
2020 Gas 22–23 MPG $3,570–$3,680 Ratings changed
2019 Gas 24 MPG $3,340–$3,390 First year

What the 2021 S5 3.0L 6-cyl turbo AWD costs to drive

Per month

$288

$3,460 a year ÷ 12

Per 25 miles

$5.77

Per 100 miles

$23.07

Five years

$17,300

5 × the yearly cost, prices held at today's level

vs the small car median

$250more a year

Class median $3,210 a year, MY2021

Based on 15,000 miles a year and premium gasoline $5.36/gal (U.S. average, Sep 2026).

2021 Audi S5 MPG

Versus 2020: The most efficient configuration stays at 23 MPG. Its annual cost goes from $3,570 to $3,460, $110 less.

Gas · 3.0L
Combined
22–23 MPG
Per year
$3,460–$3,570

Gas configurations (3)

2021 Audi S5 gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
S5 (Most efficient) 3.0L 6-cyl turbo AWD 20 28 23 $3,460
Sportback 3.0L 6-cyl turbo AWD 20 28 23 $3,460
Cabriolet 3.0L 6-cyl turbo AWD 20 26 22 $3,570

3 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2020 Audi S5 MPG

22–23 MPG · $3,570–$3,680/yr

Versus 2019: The most efficient configuration moves from 24 to 23 MPG, down 1. Its annual cost goes from $3,340 to $3,570, $230 more.

Gas · 3.0L
Combined
22–23 MPG
Per year
$3,570–$3,680

Gas configurations (3)

2020 Audi S5 gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
S5 (Most efficient) 3.0L 6-cyl turbo AWD 20 27 23 $3,570
Sportback 3.0L 6-cyl turbo AWD 20 27 23 $3,570
Cabriolet 3.0L 6-cyl turbo AWD 19 26 22 $3,680

3 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2019 Audi S5 MPG

24 MPG · $3,340–$3,390/yr
Gas · 3.0L
Combined
24 MPG
Per year
$3,340–$3,390

Gas configurations (3)

2019 Audi S5 gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
S5 (Most efficient) 3.0L 6-cyl turbo AWD 21 30 24 $3,340
Sportback 3.0L 6-cyl turbo AWD 21 30 24 $3,340
Cabriolet 3.0L 6-cyl turbo AWD 21 29 24 $3,390

3 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

Fuel cost by state

Yearly cost of the S5 3.0L 6-cyl turbo AWD: $4,120 in California and $3,000 in Texas, a $1,120 difference.

Gasoline prices: California: California state average; Washington: Washington state average; New York: New York state average; Florida: Florida state average; Texas: Texas state average (Sep 2026).
Fuel cost in every state

Similar cars

Closest combined MPG among MY2021 small car models.

EPA ratings: fueleconomy.gov file of Sep 29, 2026 · Prices: EIA regular gasoline, U.S. average, Sep 2026 ($4.36/gal) · 15,000 mi/yr, 55% city / 45% highway · How we calculate

Generations

Frequently asked questions

What gas mileage does the 2019-2021 Audi S5 get?

EPA rates the 2019-2021 Audi S5 at 22–24 MPG combined across 9 configurations and 3 model years. The most efficient version, the 2019 S5 3.0L 6-cyl turbo AWD, is rated 24 MPG (21 city, 30 highway).

Which years had the best MPG in the 2019-2021 Audi S5?

The S5 3.0L 6-cyl turbo AWD reached the generation's best combined rating, 24 MPG, in 2019. The lowest top rating, 23 MPG, was in 2020 and 2021.

Did EPA ratings change during the 2019-2021 Audi S5?

Yes. Ratings changed in 2020 and 2021.

How does the 2019-2021 Audi S5 compare with the previous generation?

The previous generation (2018 Audi S5) is rated 23–24 MPG combined and costs $3,380–$3,470 a year to fuel; the 2019-2021 model is rated 22–24 MPG and costs $3,340–$3,680 a year.

How much does it cost to fuel a 2021 Audi S5 per year?

Driving 15,000 miles a year at premium gasoline $5.36/gal (U.S. average, Sep 2026), the S5 3.0L 6-cyl turbo AWD costs about $3,460 a year. Across all 3 configurations the cost runs $3,460–$3,570 a year. That is a $110 difference between the cheapest and the costliest configuration.

How much does it cost to drive a 2021 Audi S5 100 miles?

About $23.07 per 100 miles for the S5 3.0L 6-cyl turbo AWD at premium gasoline $5.36/gal (U.S. average, Sep 2026), and between $23.07 and $23.80 across all configurations. That is the annual cost over 15,000 miles divided by 150.

Is the 2021 Audi S5 more efficient in the city or on the highway?

The S5 3.0L 6-cyl turbo AWD is rated 20 city and 28 highway MPG, so it is more efficient on the highway, by 8 MPG.

How does the 2021 Audi S5 compare with other small car configurations?

The S5 3.0L 6-cyl turbo AWD costs about $3,460 a year to fuel, $250 more than the class median of $3,210, and less than 4 of 10 small car configurations. The comparison covers all 298 rated small car configurations for MY2021, not weighted by sales.

Is the 2021 Audi S5 different from the 2020 model?

The most efficient configuration stays at 23 MPG. Its annual cost goes from $3,570 to $3,460, $110 less. EPA lists 3 configurations for 2021 against 3 configurations for 2020. See the 2020 Audi S5 for that year.