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  • Newest year: 2021
  • Gas
  • Small cars

2019-2021 Audi S4 MPG & Fuel Cost

3 model years · 23–24 MPG combined

23 MPG
Combined
20 MPG
City
28 MPG
Highway
Annual fuel cost · S4 3.0L 6-cyl turbo AWD
$3,460

15,000 mi/yr · premium gasoline $5.36/gal (U.S. average, Sep 2026)

Cheaper to fuel than 4 of 10 small car configurations, MY2021. Ranked against all rated configurations, not sales-weighted.

2019-2021 Audi S4 at a glance

The 2019-2021 Audi S4 covers 3 model years in the EPA database (3 configurations in all), rated 23–24 MPG combined. The newest model year, 2021, costs about $3,460 a year to fuel for its most efficient version, the S4 3.0L 6-cyl turbo AWD (23 MPG), at premium gasoline $5.36/gal (U.S. average, Sep 2026). EPA changed the ratings in 2020 and 2021. The best combined rating in the generation, 24 MPG, was reached in 2019.

2019-2021 Audi S4 by model year

2019-2021 Audi S4: EPA combined rating and yearly fuel cost for each model year
Model yearPowertrainsCombined$/yrEPA ratings
2021 Gas 23 MPG $3,460 Ratings changed
2020 Gas 23 MPG $3,570 Ratings changed
2019 Gas 24 MPG $3,340 First year

What the 2021 S4 3.0L 6-cyl turbo AWD costs to drive

Per month

$288

$3,460 a year ÷ 12

Per 25 miles

$5.77

Per 100 miles

$23.07

Five years

$17,300

5 × the yearly cost, prices held at today's level

vs the small car median

$250more a year

Class median $3,210 a year, MY2021

Based on 15,000 miles a year and premium gasoline $5.36/gal (U.S. average, Sep 2026).

2021 Audi S4 MPG

Versus 2020: The most efficient configuration stays at 23 MPG. Its annual cost goes from $3,570 to $3,460, $110 less.

Gas · 3.0L
Combined
23 MPG
Per year
$3,460

Gas configurations (1)

2021 Audi S4 gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
S4 (Most efficient) 3.0L 6-cyl turbo AWD 20 28 23 $3,460

1 configuration requires or recommends higher-octane gasoline and is costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2020 Audi S4 MPG

23 MPG · $3,570/yr

Versus 2019: The most efficient configuration moves from 24 to 23 MPG, down 1. Its annual cost goes from $3,340 to $3,570, $230 more.

Gas · 3.0L
Combined
23 MPG
Per year
$3,570

Gas configurations (1)

2020 Audi S4 gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
S4 (Most efficient) 3.0L 6-cyl turbo AWD 20 27 23 $3,570

1 configuration requires or recommends higher-octane gasoline and is costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2019 Audi S4 MPG

24 MPG · $3,340/yr
Gas · 3.0L
Combined
24 MPG
Per year
$3,340

Gas configurations (1)

2019 Audi S4 gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
S4 (Most efficient) 3.0L 6-cyl turbo AWD 21 30 24 $3,340

1 configuration requires or recommends higher-octane gasoline and is costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

Fuel cost by state

Yearly cost of the S4 3.0L 6-cyl turbo AWD: $4,120 in California and $3,000 in Texas, a $1,120 difference.

Gasoline prices: California: California state average; Washington: Washington state average; New York: New York state average; Florida: Florida state average; Texas: Texas state average (Sep 2026).
Fuel cost in every state

Similar cars

Closest combined MPG among MY2021 small car models.

EPA ratings: fueleconomy.gov file of Sep 29, 2026 · Prices: EIA regular gasoline, U.S. average, Sep 2026 ($4.36/gal) · 15,000 mi/yr, 55% city / 45% highway · How we calculate

Generations

Frequently asked questions

What gas mileage does the 2019-2021 Audi S4 get?

EPA rates the 2019-2021 Audi S4 at 23–24 MPG combined across 3 configurations and 3 model years. The most efficient version, the 2019 S4 3.0L 6-cyl turbo AWD, is rated 24 MPG (21 city, 30 highway).

Which years had the best MPG in the 2019-2021 Audi S4?

The S4 3.0L 6-cyl turbo AWD reached the generation's best combined rating, 24 MPG, in 2019. The lowest top rating, 23 MPG, was in 2020 and 2021.

Did EPA ratings change during the 2019-2021 Audi S4?

Yes. Ratings changed in 2020 and 2021.

How does the 2019-2021 Audi S4 compare with the previous generation?

The previous generation (2018 Audi S4) is rated 24 MPG combined and costs $3,380 a year to fuel; the 2019-2021 model is rated 23–24 MPG and costs $3,340–$3,570 a year.

How much does it cost to fuel a 2021 Audi S4 per year?

Driving 15,000 miles a year at premium gasoline $5.36/gal (U.S. average, Sep 2026), the S4 3.0L 6-cyl turbo AWD costs about $3,460 a year. Across all 1 configuration the cost runs $3,460 a year.

How much does it cost to drive a 2021 Audi S4 100 miles?

About $23.07 per 100 miles for the S4 3.0L 6-cyl turbo AWD at premium gasoline $5.36/gal (U.S. average, Sep 2026). That is the annual cost over 15,000 miles divided by 150.

Is the 2021 Audi S4 more efficient in the city or on the highway?

The S4 3.0L 6-cyl turbo AWD is rated 20 city and 28 highway MPG, so it is more efficient on the highway, by 8 MPG.

How does the 2021 Audi S4 compare with other small car configurations?

The S4 3.0L 6-cyl turbo AWD costs about $3,460 a year to fuel, $250 more than the class median of $3,210, and less than 4 of 10 small car configurations. The comparison covers all 298 rated small car configurations for MY2021, not weighted by sales.

Is the 2021 Audi S4 different from the 2020 model?

The most efficient configuration stays at 23 MPG. Its annual cost goes from $3,570 to $3,460, $110 less. EPA lists 1 configuration for 2021 against 1 configuration for 2020. See the 2020 Audi S4 for that year.