- Newest year: 2006
- Gas
- Small cars
2005-2006 Mercedes-Benz CLK-Class MPG & Fuel Cost
2 model years · 16–21 MPG combined
15,000 mi/yr · premium gasoline $5.36/gal (U.S. average, Sep 2026)
Cheaper to fuel than 3 of 10 small car configurations, MY2006. Ranked against all rated configurations, not sales-weighted.
2005-2006 Mercedes-Benz CLK-Class at a glance
The 2005-2006 Mercedes-Benz CLK-Class covers 2 model years in the EPA database (11 configurations in all), rated 16–21 MPG combined. The newest model year, 2006, costs about $4,020 a year to fuel for its most efficient version, the CLK350 3.5L 6-cyl RWD (20 MPG), at premium gasoline $5.36/gal (U.S. average, Sep 2026). EPA changed the ratings in 2006. The best combined rating in the generation, 21 MPG, was reached in 2005.
EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.
2005-2006 Mercedes-Benz CLK-Class by model year
What the 2006 CLK350 3.5L 6-cyl RWD costs to drive
Per month
$335
$4,020 a year ÷ 12
Per 25 miles
$6.70
Per 100 miles
$26.80
Five years
$20,100
5 × the yearly cost, prices held at today's level
vs the small car median
$370more a year
Class median $3,650 a year, MY2006
Based on 15,000 miles a year and premium gasoline $5.36/gal (U.S. average, Sep 2026).
2006 Mercedes-Benz CLK-Class MPG
EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.
Versus 2005: The most efficient configuration moves from 21 to 20 MPG, down 1. Its annual cost goes from $3,830 to $4,020, $190 more.
Gas configurations (5)
| Trim | Engine | Drive | City | Hwy | Comb. | $/yr |
|---|---|---|---|---|---|---|
| CLK350 (Most efficient) | 3.5L 6-cyl | RWD | 17 | 26 | 20 | $4,020 |
| CLK350 (Cabriolet) | 3.5L 6-cyl | RWD | 16 | 24 | 19 | $4,230 |
| CLK500 | 5.0L 8-cyl | RWD | 15 | 23 | 18 | $4,460 |
| CLK500 (Cabriolet) | 5.0L 8-cyl | RWD | 15 | 23 | 18 | $4,460 |
| CLK55 AMG (Cabriolet) | 5.4L 8-cyl | RWD | 15 | 21 | 17 | $4,730 |
5 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).
2005 Mercedes-Benz CLK-Class MPG
16–21 MPG · $3,830–$5,020/yr
EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.
Gas configurations (6)
| Trim | Engine | Drive | City | Hwy | Comb. | $/yr |
|---|---|---|---|---|---|---|
| CLK320 (Most efficient) | 3.2L 6-cyl | RWD | 18 | 26 | 21 | $3,830 |
| CLK320 (Cabriolet) | 3.2L 6-cyl | RWD | 18 | 24 | 20 | $4,020 |
| CLK500 | 5.0L 8-cyl | RWD | 15 | 23 | 18 | $4,460 |
| CLK500 (Cabriolet) | 5.0L 8-cyl | RWD | 15 | 23 | 18 | $4,460 |
| CLK55 AMG | 5.4L 8-cyl | RWD | 14 | 21 | 17 | $4,730 |
| CLK55 AMG (Cabriolet) | 5.4L 8-cyl | RWD | 14 | 21 | 16 | $5,020 |
6 configurations require or recommend higher-octane gasoline and are costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).
Fuel cost by state
Yearly cost of the CLK350 3.5L 6-cyl RWD: $4,790 in California and $3,480 in Texas, a $1,310 difference.
- California $4,790
- Washington $4,510
- New York $3,970
- Florida $3,670
- Texas $3,480
Similar cars
Closest combined MPG among MY2006 small car models.
Generations
Frequently asked questions
What gas mileage does the 2005-2006 Mercedes-Benz CLK-Class get?
EPA rates the 2005-2006 Mercedes-Benz CLK-Class at 16–21 MPG combined across 11 configurations and 2 model years. The most efficient version, the 2005 CLK320 3.2L 6-cyl RWD, is rated 21 MPG (18 city, 26 highway).
Which years had the best MPG in the 2005-2006 Mercedes-Benz CLK-Class?
The CLK320 3.2L 6-cyl RWD reached the generation's best combined rating, 21 MPG, in 2005. The lowest top rating, 20 MPG, was in 2006.
Did EPA ratings change during the 2005-2006 Mercedes-Benz CLK-Class?
Yes. Ratings changed in 2006.
How does the 2005-2006 Mercedes-Benz CLK-Class compare with the previous generation?
The previous generation (2004 Mercedes-Benz CLK-Class) is rated 16–20 MPG combined and costs $4,020–$5,020 a year to fuel; the 2005-2006 model is rated 16–21 MPG and costs $3,830–$5,020 a year.
How much does it cost to fuel a 2006 Mercedes-Benz CLK-Class per year?
Driving 15,000 miles a year at premium gasoline $5.36/gal (U.S. average, Sep 2026), the CLK350 3.5L 6-cyl RWD costs about $4,020 a year. Across all 5 configurations the cost runs $4,020–$4,730 a year. That is a $710 difference between the cheapest and the costliest configuration.
How much does it cost to drive a 2006 Mercedes-Benz CLK-Class 100 miles?
About $26.80 per 100 miles for the CLK350 3.5L 6-cyl RWD at premium gasoline $5.36/gal (U.S. average, Sep 2026), and between $26.80 and $31.53 across all configurations. That is the annual cost over 15,000 miles divided by 150.
Is the 2006 Mercedes-Benz CLK-Class more efficient in the city or on the highway?
The CLK350 3.5L 6-cyl RWD is rated 17 city and 26 highway MPG, so it is more efficient on the highway, by 9 MPG.
How does the 2006 Mercedes-Benz CLK-Class compare with other small car configurations?
The CLK350 3.5L 6-cyl RWD costs about $4,020 a year to fuel, $370 more than the class median of $3,650, and less than 3 of 10 small car configurations. The comparison covers all 286 rated small car configurations for MY2006, not weighted by sales.
Is the 2006 Mercedes-Benz CLK-Class different from the 2005 model?
The most efficient configuration moves from 21 to 20 MPG, down 1. Its annual cost goes from $3,830 to $4,020, $190 more. EPA lists 5 configurations for 2006 against 6 configurations for 2005. See the 2005 Mercedes-Benz CLK-Class for that year.