- Gas
- Standard pickups
- MY2006–2006
Isuzu i-280 Extended Cab MPG & Fuel Cost by Year
1 model years · 2006–2006
15,000 mi/yr · regular gasoline $4.36/gal (U.S. average, Sep 2026)
Isuzu i-280 Extended Cab fuel economy at a glance
EPA has rated the Isuzu i-280 Extended Cab for 1 model years, 2006 to 2006. Across those years its combined rating runs 17–21 MPG. The latest model year, 2006, has 2 configurations rated 17–21 MPG combined and costing $3,110–$3,840 a year to fuel at regular gasoline $4.36/gal (U.S. average, Sep 2026). The most efficient configuration on record since 2006 is the 2006 i-280 Extended Cab 2.8L 4-cyl RWD, at 21 MPG.
Isuzu i-280 Extended Cab MPG by year
| Year | Gas (MPG) | $/yr |
|---|---|---|
| 2006 Generation page | ||
| 2006 | 17–21 | $3,110–$3,840 |
Costs use the current EIA price set and 15,000 miles a year for every year, so years are comparable. Green marks the best year for each powertrain.
Isuzu i-280 Extended Cab generations
1 generations between 2006 and 2006. Open one for the table of every model year and configuration.
2006 powertrain options
More Isuzu models
Frequently asked questions
What is the Isuzu i-280 Extended Cab's gas mileage by year?
EPA combined ratings for the Isuzu i-280 Extended Cab run 17–21 MPG across model years 2006 to 2006. The latest year, 2006, is rated 17–21 MPG.
Which Isuzu i-280 Extended Cab model year has the best gas mileage?
The 2006 Isuzu i-280 Extended Cab i-280 Extended Cab 2.8L 4-cyl RWD has the highest combined rating since 2006, at 21 MPG.
How much does a Isuzu i-280 Extended Cab cost to fuel per year?
For MY2006, EPA-rated configurations cost $3,110–$3,840 a year to fuel, driving 15,000 miles at regular gasoline $4.36/gal (U.S. average, Sep 2026). The most efficient one costs $3,110.