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2010 Honda Odyssey LX 3.5L (RL3)
Shown: 2010 Honda Odyssey LX 3.5L (RL3). Photo: Kevauto, CC BY-SA 4.0, via Wikimedia Commons
  • Newest year: 2010
  • Gas
  • Minivans
  • Same as 2009

2005-2010 Honda Odyssey MPG & Fuel Cost

6 model years · 18–20 MPG combined

20 MPG
Combined
17 MPG
City
25 MPG
Highway
Annual fuel cost · Odyssey 3.5L 6-cyl FWD
$3,270

15,000 mi/yr · regular gasoline $4.36/gal (U.S. average, Sep 2026)

2005-2010 Honda Odyssey at a glance

The 2005-2010 Honda Odyssey covers 6 model years in the EPA database (12 configurations in all), rated 18–20 MPG combined. The newest model year, 2010, costs about $3,270 a year to fuel for its most efficient version, the Odyssey 3.5L 6-cyl FWD (20 MPG), at regular gasoline $4.36/gal (U.S. average, Sep 2026). EPA changed the ratings in 2007 and 2008; 2006, 2009 and 2010 repeat the values of the year before. The best combined rating in the generation, 20 MPG, was reached in 2005, 2006, 2008, 2009 and 2010.

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

2005-2010 Honda Odyssey by model year

2005-2010 Honda Odyssey: EPA combined rating and yearly fuel cost for each model year
Model yearPowertrainsCombined$/yrEPA ratings
2010 Gas 18–20 MPG $3,270–$3,630 Same EPA ratings as 2009
2009 Gas 18–20 MPG $3,270–$3,630 Same EPA ratings as 2008
2008 Gas 18–20 MPG $3,270–$3,630 Ratings changed
2007 Gas 18–19 MPG $3,440–$3,630 Ratings changed
2006 Gas 19–20 MPG $3,270–$3,440 Same EPA ratings as 2005
2005 Gas 19–20 MPG $3,270–$3,440 First year

What the 2010 Odyssey 3.5L 6-cyl FWD costs to drive

Per month

$273

$3,270 a year ÷ 12

Per 25 miles

$5.45

Per 100 miles

$21.80

Five years

$16,350

5 × the yearly cost, prices held at today's level

Based on 15,000 miles a year and regular gasoline $4.36/gal (U.S. average, Sep 2026).

2010 Honda Odyssey MPG

EPA lists the same ratings for the 2010 Honda Odyssey as for the 2009 model, so the configurations and costs are the ones in the 2009 section above.See 2009

Gas · 3.5L
Combined
18–20 MPG
Per year
$3,270–$3,630

Gas configurations (2)

2010 Honda Odyssey gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
Odyssey 3.5L 6-cyl FWD Automatic 5-spd (Most efficient) 3.5L 6-cyl FWD 17 25 20 $3,270
Odyssey 3.5L 6-cyl FWD Automatic 5-spd 3.5L 6-cyl FWD 16 23 18 $3,630

2009 Honda Odyssey MPG

Same EPA ratings as 2008

EPA lists the same ratings for the 2009 Honda Odyssey as for the 2008 model, so the configurations and costs are the ones in the 2008 section above.See 2008

2008 Honda Odyssey MPG

18–20 MPG · $3,270–$3,630/yr

Versus 2007: The most efficient configuration moves from 19 to 20 MPG, up 1. Its annual cost goes from $3,440 to $3,270, $170 less.

Gas · 3.5L
Combined
18–20 MPG
Per year
$3,270–$3,630

Gas configurations (2)

2008 Honda Odyssey gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
Odyssey 3.5L 6-cyl FWD Automatic 5-spd (Most efficient) 3.5L 6-cyl FWD 17 25 20 $3,270
Odyssey 3.5L 6-cyl FWD Automatic 5-spd 3.5L 6-cyl FWD 16 23 18 $3,630

2007 Honda Odyssey MPG

18–19 MPG · $3,440–$3,630/yr

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

Versus 2006: The most efficient configuration moves from 20 to 19 MPG, down 1. Its annual cost goes from $3,270 to $3,440, $170 more.

Gas · 3.5L
Combined
18–19 MPG
Per year
$3,440–$3,630

Gas configurations (2)

2007 Honda Odyssey gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
Odyssey 3.5L 6-cyl FWD Automatic 5-spd (Most efficient) 3.5L 6-cyl FWD 17 24 19 $3,440
Odyssey 3.5L 6-cyl FWD Automatic 5-spd 3.5L 6-cyl FWD 16 23 18 $3,630

2006 Honda Odyssey MPG

Same EPA ratings as 2005

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

EPA lists the same ratings for the 2006 Honda Odyssey as for the 2005 model, so the configurations and costs are the ones in the 2005 section above.See 2005

2005 Honda Odyssey MPG

19–20 MPG · $3,270–$3,440/yr

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

Gas · 3.5L
Combined
19–20 MPG
Per year
$3,270–$3,440

Gas configurations (2)

2005 Honda Odyssey gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
Odyssey 3.5L 6-cyl FWD Automatic 5-spd (Most efficient) 3.5L 6-cyl FWD 17 26 20 $3,270
Odyssey 3.5L 6-cyl FWD Automatic 5-spd 3.5L 6-cyl FWD 17 23 19 $3,440

Fuel cost by state

Yearly cost of the Odyssey 3.5L 6-cyl FWD: $4,440 in California and $2,850 in Texas, a $1,590 difference.

Gasoline prices: California: California state average; Washington: Washington state average; New York: New York state average; Florida: Florida state average; Texas: Texas state average (Sep 2026).
Fuel cost in every state

Similar cars

Closest combined MPG among MY2010 minivan models.

EPA ratings: fueleconomy.gov file of Sep 29, 2026 · Prices: EIA regular gasoline, U.S. average, Sep 2026 ($4.36/gal) · 15,000 mi/yr, 55% city / 45% highway · How we calculate

Generations

Frequently asked questions

What gas mileage does the 2005-2010 Honda Odyssey get?

EPA rates the 2005-2010 Honda Odyssey at 18–20 MPG combined across 12 configurations and 6 model years. The most efficient version, the 2010 Odyssey 3.5L 6-cyl FWD, is rated 20 MPG (17 city, 25 highway).

Which years had the best MPG in the 2005-2010 Honda Odyssey?

The Odyssey 3.5L 6-cyl FWD reached the generation's best combined rating, 20 MPG, in 2005, 2006, 2008, 2009 and 2010. The lowest top rating, 19 MPG, was in 2007.

Did EPA ratings change during the 2005-2010 Honda Odyssey?

Yes. Ratings changed in 2007 and 2008. In 2006, 2009 and 2010 the values repeat the year before.

How does the 2005-2010 Honda Odyssey compare with the previous generation?

The previous generation (2000-2004 Honda Odyssey) is rated 18–19 MPG combined and costs $3,440–$3,630 a year to fuel; the 2005-2010 model is rated 18–20 MPG and costs $3,270–$3,630 a year.

How much does it cost to fuel a 2010 Honda Odyssey per year?

Driving 15,000 miles a year at regular gasoline $4.36/gal (U.S. average, Sep 2026), the Odyssey 3.5L 6-cyl FWD costs about $3,270 a year. Across all 2 configurations the cost runs $3,270–$3,630 a year. That is a $360 difference between the cheapest and the costliest configuration.

How much does it cost to drive a 2010 Honda Odyssey 100 miles?

About $21.80 per 100 miles for the Odyssey 3.5L 6-cyl FWD at regular gasoline $4.36/gal (U.S. average, Sep 2026), and between $21.80 and $24.20 across all configurations. That is the annual cost over 15,000 miles divided by 150.

Is the 2010 Honda Odyssey more efficient in the city or on the highway?

The Odyssey 3.5L 6-cyl FWD is rated 17 city and 25 highway MPG, so it is more efficient on the highway, by 8 MPG.

Is the 2010 Honda Odyssey different from the 2009 model?

No. EPA lists the same ratings for 2009 and 2010: 2 configurations rated 18–20 MPG combined. See the 2009 Honda Odyssey for that year.