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2006 Ford E-150 Van Commercial
Shown: 2006 Ford E-150 Van Commercial. Photo: MercurySable99, CC BY-SA 4.0, via Wikimedia Commons
  • Newest year: 2006
  • Gas
  • Vans

2000-2006 Ford E150 Econoline MPG & Fuel Cost

7 model years · 13–16 MPG combined

15 MPG
Combined
13 MPG
City
17 MPG
Highway
Annual fuel cost · E150 Econoline 4.6L 8-cyl RWD
$4,360

15,000 mi/yr · regular gasoline $4.36/gal (U.S. average, Sep 2026)

Cheaper to fuel than 6 of 10 van configurations, MY2006. Ranked against all rated configurations, not sales-weighted.

2000-2006 Ford E150 Econoline at a glance

The 2000-2006 Ford E150 Econoline covers 7 model years in the EPA database (18 configurations in all), rated 13–16 MPG combined. The newest model year, 2006, costs about $4,360 a year to fuel for its most efficient version, the E150 Econoline 4.6L 8-cyl RWD (15 MPG), at regular gasoline $4.36/gal (U.S. average, Sep 2026). EPA changed the ratings in 2001, 2002, 2003, 2004 and 2006; 2005 repeat the values of the year before. The best combined rating in the generation, 16 MPG, was reached in 2001, 2002 and 2003.

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

2000-2006 Ford E150 Econoline by model year

2000-2006 Ford E150 Econoline: EPA combined rating and yearly fuel cost for each model year
Model yearPowertrainsCombined$/yrEPA ratings
2006 Gas 14–15 MPG $4,360–$4,670 Ratings changed
2005 Gas 14–15 MPG $4,360–$4,670 Same EPA ratings as 2004
2004 Gas 14–15 MPG $4,360–$4,670 Ratings changed
2003 Gas 13–16 MPG $4,080–$5,030 Ratings changed
2002 Gas 14–16 MPG $4,080–$4,670 Ratings changed
2001 Gas 14–16 MPG $4,080–$4,670 Ratings changed
2000 Gas 14–15 MPG $4,360–$4,670 First year

What the 2006 E150 Econoline 4.6L 8-cyl RWD costs to drive

Per month

$363

$4,360 a year ÷ 12

Per 25 miles

$7.27

Per 100 miles

$29.07

Five years

$21,800

5 × the yearly cost, prices held at today's level

vs the van median

$310less a year

Class median $4,670 a year, MY2006

Based on 15,000 miles a year and regular gasoline $4.36/gal (U.S. average, Sep 2026).

2006 Ford E150 Econoline MPG

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

Versus 2005: The most efficient configuration stays at 15 MPG. Its annual cost stays at $4,360.

Gas · 4.6L, 5.4L
Combined
14–15 MPG
Per year
$4,360–$4,670

Gas configurations (2)

2006 Ford E150 Econoline gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
E150 Econoline 4.6L 8-cyl (Most efficient) 4.6L 8-cyl RWD 13 17 15 $4,360
E150 Econoline 5.4L 8-cyl 5.4L 8-cyl RWD 13 16 14 $4,670

2005 Ford E150 Econoline MPG

Same EPA ratings as 2004

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

EPA lists the same ratings for the 2005 Ford E150 Econoline as for the 2004 model, so the configurations and costs are the ones in the 2004 section above.See 2004

2004 Ford E150 Econoline MPG

14–15 MPG · $4,360–$4,670/yr

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

Versus 2003: The most efficient configuration moves from 16 to 15 MPG, down 1. Its annual cost goes from $4,080 to $4,360, $280 more.

Gas · 4.6L, 5.4L
Combined
14–15 MPG
Per year
$4,360–$4,670

Gas configurations (2)

2004 Ford E150 Econoline gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
E150 Econoline 4.6L 8-cyl (Most efficient) 4.6L 8-cyl RWD 13 18 15 $4,360
E150 Econoline 5.4L 8-cyl 5.4L 8-cyl RWD 13 16 14 $4,670

2003 Ford E150 Econoline MPG

13–16 MPG · $4,080–$5,030/yr

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

Versus 2002: The most efficient configuration stays at 16 MPG. Its annual cost stays at $4,080.

Gas · 4.2L, 4.6L, 5.4L
Combined
13–16 MPG
Per year
$4,080–$5,030

Gas configurations (3)

2003 Ford E150 Econoline gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
E150 Econoline 4.6L 8-cyl (Most efficient) 4.6L 8-cyl RWD 14 19 16 $4,080
E150 Econoline 4.2L 6-cyl 4.2L 6-cyl RWD 13 17 15 $4,360
E150 Econoline 5.4L 8-cyl 5.4L 8-cyl RWD 12 15 13 $5,030

2002 Ford E150 Econoline MPG

14–16 MPG · $4,080–$4,670/yr

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

Versus 2001: The most efficient configuration stays at 16 MPG. Its annual cost stays at $4,080.

Gas · 4.2L, 4.6L, 5.4L
Combined
14–16 MPG
Per year
$4,080–$4,670

Gas configurations (3)

2002 Ford E150 Econoline gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
E150 Econoline 4.6L 8-cyl (Most efficient) 4.6L 8-cyl RWD 14 19 16 $4,080
E150 Econoline 5.4L 8-cyl 5.4L 8-cyl RWD 13 18 15 $4,360
E150 Econoline 4.2L 6-cyl 4.2L 6-cyl RWD 13 17 14 $4,670

2001 Ford E150 Econoline MPG

14–16 MPG · $4,080–$4,670/yr

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

Versus 2000: The most efficient configuration moves from 15 to 16 MPG, up 1. Its annual cost goes from $4,360 to $4,080, $280 less.

Gas · 4.2L, 4.6L, 5.4L
Combined
14–16 MPG
Per year
$4,080–$4,670

Gas configurations (3)

2001 Ford E150 Econoline gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
E150 Econoline 4.6L 8-cyl (Most efficient) 4.6L 8-cyl RWD 14 19 16 $4,080
E150 Econoline 5.4L 8-cyl 5.4L 8-cyl RWD 13 18 15 $4,360
E150 Econoline 4.2L 6-cyl 4.2L 6-cyl RWD 13 18 14 $4,670

2000 Ford E150 Econoline MPG

14–15 MPG · $4,360–$4,670/yr

EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.

Gas · 4.2L, 4.6L, 5.4L
Combined
14–15 MPG
Per year
$4,360–$4,670

Gas configurations (3)

2000 Ford E150 Econoline gas configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
E150 Econoline 4.6L 8-cyl (Most efficient) 4.6L 8-cyl RWD 13 18 15 $4,360
E150 Econoline 5.4L 8-cyl 5.4L 8-cyl RWD 13 18 15 $4,360
E150 Econoline 4.2L 6-cyl 4.2L 6-cyl RWD 13 17 14 $4,670

Fuel cost by state

Yearly cost of the E150 Econoline 4.6L 8-cyl RWD: $5,920 in California and $3,800 in Texas, a $2,120 difference.

Gasoline prices: California: California state average; Washington: Washington state average; New York: New York state average; Florida: Florida state average; Texas: Texas state average (Sep 2026).
Fuel cost in every state

Similar cars

Closest combined MPG among MY2006 van models.

EPA ratings: fueleconomy.gov file of Sep 29, 2026 · Prices: EIA regular gasoline, U.S. average, Sep 2026 ($4.36/gal) · 15,000 mi/yr, 55% city / 45% highway · How we calculate

Generations

  • 2000-2006

Frequently asked questions

What gas mileage does the 2000-2006 Ford E150 Econoline get?

EPA rates the 2000-2006 Ford E150 Econoline at 13–16 MPG combined across 18 configurations and 7 model years. The most efficient version, the 2003 E150 Econoline 4.6L 8-cyl RWD, is rated 16 MPG (14 city, 19 highway).

Which years had the best MPG in the 2000-2006 Ford E150 Econoline?

The E150 Econoline 4.6L 8-cyl RWD reached the generation's best combined rating, 16 MPG, in 2001, 2002 and 2003. The lowest top rating, 15 MPG, was in 2000, 2004, 2005 and 2006.

Did EPA ratings change during the 2000-2006 Ford E150 Econoline?

Yes. Ratings changed in 2001, 2002, 2003, 2004 and 2006. In 2005 the values repeat the year before.

How much does it cost to fuel a 2006 Ford E150 Econoline per year?

Driving 15,000 miles a year at regular gasoline $4.36/gal (U.S. average, Sep 2026), the E150 Econoline 4.6L 8-cyl RWD costs about $4,360 a year. Across all 2 configurations the cost runs $4,360–$4,670 a year. That is a $310 difference between the cheapest and the costliest configuration.

How much does it cost to drive a 2006 Ford E150 Econoline 100 miles?

About $29.07 per 100 miles for the E150 Econoline 4.6L 8-cyl RWD at regular gasoline $4.36/gal (U.S. average, Sep 2026), and between $29.07 and $31.13 across all configurations. That is the annual cost over 15,000 miles divided by 150.

Is the 2006 Ford E150 Econoline more efficient in the city or on the highway?

The E150 Econoline 4.6L 8-cyl RWD is rated 13 city and 17 highway MPG, so it is more efficient on the highway, by 4 MPG.

How does the 2006 Ford E150 Econoline compare with other van configurations?

The E150 Econoline 4.6L 8-cyl RWD costs about $4,360 a year to fuel, $310 less than the class median of $4,670, and less than 6 of 10 van configurations. The comparison covers all 22 rated van configurations for MY2006, not weighted by sales.

Is the 2006 Ford E150 Econoline different from the 2005 model?

The most efficient configuration stays at 15 MPG. Its annual cost stays at $4,360. EPA lists 2 configurations for 2006 against 2 configurations for 2005. See the 2005 Ford E150 Econoline for that year.