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2019 Audi A6 55 TFSI Quattro Progressiv Quattro S-Line (C8)
Shown: 2019 Audi A6 55 TFSI Quattro Progressiv Quattro S-Line (C8). Photo: Elise240SX, CC BY-SA 4.0, via Wikimedia Commons
  • Newest year: 2021
  • Hybrid
  • Midsize cars
  • Same as 2020

2020-2021 Audi S6 MPG & Fuel Cost

2 model years · 22 MPG combined

22 MPG
Combined
18 MPG
City
28 MPG
Highway
Annual fuel cost · S6 2.9L 6-cyl turbo AWD
$3,730

15,000 mi/yr · premium gasoline $5.36/gal (U.S. average, Sep 2026)

Cheaper to fuel than 2 of 10 midsize car configurations, MY2021. Ranked against all rated configurations, not sales-weighted.

2020-2021 Audi S6 at a glance

The 2020-2021 Audi S6 covers 2 model years in the EPA database (2 configurations in all), rated 22 MPG combined. The newest model year, 2021, costs about $3,730 a year to fuel for its most efficient version, the S6 2.9L 6-cyl turbo AWD (22 MPG), at premium gasoline $5.36/gal (U.S. average, Sep 2026). EPA lists identical ratings for every model year of this generation.

2020-2021 Audi S6 by model year

2020-2021 Audi S6: EPA combined rating and yearly fuel cost for each model year
Model yearPowertrainsCombined$/yrEPA ratings
2021 Hybrid 22 MPG $3,730 Same EPA ratings as 2020
2020 Hybrid 22 MPG $3,730 First year

What the 2021 S6 2.9L 6-cyl turbo AWD costs to drive

Per month

$311

$3,730 a year ÷ 12

Per 25 miles

$6.22

Per 100 miles

$24.87

Five years

$18,650

5 × the yearly cost, prices held at today's level

vs the midsize car median

$1,130more a year

Class median $2,600 a year, MY2021

Based on 15,000 miles a year and premium gasoline $5.36/gal (U.S. average, Sep 2026).

2021 Audi S6 MPG

EPA lists the same ratings for the 2021 Audi S6 as for the 2020 model, so the configurations and costs are the ones in the 2020 section above.See 2020

Hybrid · 2.9L
Combined
22 MPG
Per year
$3,730

Hybrid configurations (1)

2021 Audi S6 hybrid configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
S6 (Most efficient) 2.9L 6-cyl turbo AWD 18 28 22 $3,730

1 configuration requires or recommends higher-octane gasoline and is costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

2020 Audi S6 MPG

22 MPG · $3,730/yr
Hybrid · 2.9L
Combined
22 MPG
Per year
$3,730

Hybrid configurations (1)

2020 Audi S6 hybrid configurations: EPA ratings and annual cost
TrimEngineDriveCityHwyComb.$/yr
S6 (Most efficient) 2.9L 6-cyl turbo AWD 18 28 22 $3,730

1 configuration requires or recommends higher-octane gasoline and is costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).

Fuel cost by state

Yearly cost of the S6 2.9L 6-cyl turbo AWD: $4,440 in California and $3,230 in Texas, a $1,210 difference.

Gasoline prices: California: California state average; Washington: Washington state average; New York: New York state average; Florida: Florida state average; Texas: Texas state average (Sep 2026).
Fuel cost in every state

Similar cars

Closest combined MPG among MY2021 midsize car models.

EPA ratings: fueleconomy.gov file of Sep 29, 2026 · Prices: EIA regular gasoline, U.S. average, Sep 2026 ($4.36/gal) · 15,000 mi/yr, 55% city / 45% highway · How we calculate

Generations

Frequently asked questions

What gas mileage does the 2020-2021 Audi S6 get?

EPA rates the 2020-2021 Audi S6 at 22 MPG combined across 2 configurations and 2 model years. The most efficient version, the 2021 S6 2.9L 6-cyl turbo AWD, is rated 22 MPG (18 city, 28 highway).

Which years had the best MPG in the 2020-2021 Audi S6?

Every model year of the 2020-2021 Audi S6 tops out at 22 MPG combined, so no year is better than another.

Did EPA ratings change during the 2020-2021 Audi S6?

No. EPA lists the same ratings for every model year from 2020 to 2021.

How does the 2020-2021 Audi S6 compare with the previous generation?

The previous generation (2013-2018 Audi S6) is rated 18–21 MPG combined and costs $3,850–$4,360 a year to fuel; the 2020-2021 model is rated 22 MPG and costs $3,730 a year.

How much does it cost to fuel a 2021 Audi S6 per year?

Driving 15,000 miles a year at premium gasoline $5.36/gal (U.S. average, Sep 2026), the S6 2.9L 6-cyl turbo AWD costs about $3,730 a year. Across all 1 configuration the cost runs $3,730 a year.

How much does it cost to drive a 2021 Audi S6 100 miles?

About $24.87 per 100 miles for the S6 2.9L 6-cyl turbo AWD at premium gasoline $5.36/gal (U.S. average, Sep 2026). That is the annual cost over 15,000 miles divided by 150.

Is the 2021 Audi S6 more efficient in the city or on the highway?

The S6 2.9L 6-cyl turbo AWD is rated 18 city and 28 highway MPG, so it is more efficient on the highway, by 10 MPG.

How does the 2021 Audi S6 compare with other midsize car configurations?

The S6 2.9L 6-cyl turbo AWD costs about $3,730 a year to fuel, $1,130 more than the class median of $2,600, and less than 2 of 10 midsize car configurations. The comparison covers all 149 rated midsize car configurations for MY2021, not weighted by sales.

Is the 2021 Audi S6 different from the 2020 model?

No. EPA lists the same ratings for 2020 and 2021: 1 configuration rated 22 MPG combined. See the 2020 Audi S6 for that year.