- Newest year: 2006
- Gas
- Standard SUVs
- Same as 2005
2001-2006 Acura MDX MPG & Fuel Cost
6 model years · 17 MPG combined
15,000 mi/yr · premium gasoline $5.36/gal (U.S. average, Sep 2026)
Cheaper to fuel than 1 of 10 standard SUV configurations, MY2006. Ranked against all rated configurations, not sales-weighted.
2001-2006 Acura MDX at a glance
The 2001-2006 Acura MDX covers 6 model years in the EPA database (6 configurations in all), rated 17 MPG combined. The newest model year, 2006, costs about $4,730 a year to fuel for its most efficient version, the MDX 3.5L 6-cyl 4WD (17 MPG), at premium gasoline $5.36/gal (U.S. average, Sep 2026). EPA lists identical ratings for every model year of this generation.
EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.
2001-2006 Acura MDX by model year
| Model year | Powertrains | Combined | $/yr | EPA ratings |
|---|---|---|---|---|
| 2006 | Gas | 17 MPG | $4,730 | Same EPA ratings as 2005 |
| 2005 | Gas | 17 MPG | $4,730 | Same EPA ratings as 2004 |
| 2004 | Gas | 17 MPG | $4,730 | Same EPA ratings as 2003 |
| 2003 | Gas | 17 MPG | $4,730 | Same EPA ratings as 2002 |
| 2002 | Gas | 17 MPG | $4,730 | Same EPA ratings as 2001 |
| 2001 | Gas | 17 MPG | $4,730 | First year |
What the 2006 MDX 3.5L 6-cyl 4WD costs to drive
Per month
$394
$4,730 a year ÷ 12
Per 25 miles
$7.88
Per 100 miles
$31.53
Five years
$23,650
5 × the yearly cost, prices held at today's level
vs the standard SUV median
$650more a year
Class median $4,080 a year, MY2006
Based on 15,000 miles a year and premium gasoline $5.36/gal (U.S. average, Sep 2026).
2006 Acura MDX MPG
EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.
EPA lists the same ratings for the 2006 Acura MDX as for the 2005 model, so the configurations and costs are the ones in the 2005 section above.See 2005
Gas configurations (1)
| Trim | Engine | Drive | City | Hwy | Comb. | $/yr |
|---|---|---|---|---|---|---|
| MDX (Most efficient) | 3.5L 6-cyl | 4WD | 15 | 21 | 17 | $4,730 |
1 configuration requires or recommends higher-octane gasoline and is costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).
2005 Acura MDX MPG
Same EPA ratings as 2004
EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.
EPA lists the same ratings for the 2005 Acura MDX as for the 2004 model, so the configurations and costs are the ones in the 2004 section above.See 2004
2004 Acura MDX MPG
Same EPA ratings as 2003
EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.
EPA lists the same ratings for the 2004 Acura MDX as for the 2003 model, so the configurations and costs are the ones in the 2003 section above.See 2003
2003 Acura MDX MPG
Same EPA ratings as 2002
EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.
EPA lists the same ratings for the 2003 Acura MDX as for the 2002 model, so the configurations and costs are the ones in the 2002 section above.See 2002
2002 Acura MDX MPG
Same EPA ratings as 2001
EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.
EPA lists the same ratings for the 2002 Acura MDX as for the 2001 model, so the configurations and costs are the ones in the 2001 section above.See 2001
2001 Acura MDX MPG
17 MPG · $4,730/yr
EPA re-estimated ratings of 1985-2007 vehicles under its 2008 method; these figures are the re-estimated values.
Gas configurations (1)
| Trim | Engine | Drive | City | Hwy | Comb. | $/yr |
|---|---|---|---|---|---|---|
| MDX (Most efficient) | 3.5L 6-cyl | 4WD | 15 | 21 | 17 | $4,730 |
1 configuration requires or recommends higher-octane gasoline and is costed at premium gasoline $5.36/gal (U.S. average, Sep 2026).
Fuel cost by state
Yearly cost of the MDX 3.5L 6-cyl 4WD: $5,640 in California and $4,100 in Texas, a $1,540 difference.
- California $5,640
- Washington $5,300
- New York $4,670
- Florida $4,320
- Texas $4,100
Similar cars
Closest combined MPG among MY2006 standard SUV models.
Generations
- 2001-2006 (YD1)
- 2007-2013 (YD2)
- 2014-2020 (3rd gen)
- 2022-2026 (4th gen)
Frequently asked questions
What gas mileage does the 2001-2006 Acura MDX get?
EPA rates the 2001-2006 Acura MDX at 17 MPG combined across 6 configurations and 6 model years. The most efficient version, the 2006 MDX 3.5L 6-cyl 4WD, is rated 17 MPG (15 city, 21 highway).
Which years had the best MPG in the 2001-2006 Acura MDX?
Every model year of the 2001-2006 Acura MDX tops out at 17 MPG combined, so no year is better than another.
Did EPA ratings change during the 2001-2006 Acura MDX?
No. EPA lists the same ratings for every model year from 2001 to 2006.
How much does it cost to fuel a 2006 Acura MDX per year?
Driving 15,000 miles a year at premium gasoline $5.36/gal (U.S. average, Sep 2026), the MDX 3.5L 6-cyl 4WD costs about $4,730 a year. Across all 1 configuration the cost runs $4,730 a year.
How much does it cost to drive a 2006 Acura MDX 100 miles?
About $31.53 per 100 miles for the MDX 3.5L 6-cyl 4WD at premium gasoline $5.36/gal (U.S. average, Sep 2026). That is the annual cost over 15,000 miles divided by 150.
Is the 2006 Acura MDX more efficient in the city or on the highway?
The MDX 3.5L 6-cyl 4WD is rated 15 city and 21 highway MPG, so it is more efficient on the highway, by 6 MPG.
How does the 2006 Acura MDX compare with other standard SUV configurations?
The MDX 3.5L 6-cyl 4WD costs about $4,730 a year to fuel, $650 more than the class median of $4,080, and less than 1 of 10 standard SUV configurations. The comparison covers all 296 rated standard SUV configurations for MY2006, not weighted by sales.
Is the 2006 Acura MDX different from the 2005 model?
No. EPA lists the same ratings for 2005 and 2006: 1 configuration rated 17 MPG combined. See the 2005 Acura MDX for that year.